Mostrando 10 resultados de: 17
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Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology(1)
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Cruzioseptins, antibacterial peptides from Cruziohyla calcarifer skin, as promising leishmanicidal agents
ArticleAbstract: Screenings of natural products have significantly contributed to the discovery of novel leishmanicidPalabras claves:Cruzioseptins, Frog skin secretion, Leishmanicidal, PeptidesAutores:Bruno Mendes, Carolina Proaño-Bolaños, Gadelha F.R., Jose Rafael de Almeida, Miguel D.C.Fuentes:googleorcidscopusPotential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents
ArticleAbstract: Phospholipase A<inf>2</inf> toxins present in snake venoms interact with biological membranes and sePalabras claves:Leishmanicidal activity, Oligoarginine, peptide, PhospholipaseAutores:Bruno Mendes, Gadelha F.R., Gomes P.A.D.C., Jose Rafael de Almeida, Miguel D.C., Saulo L. Silva, Vale N.Fuentes:googleorcidscopusMolecular detection of Trypanosoma cruzi in reservoir hosts by quantitative polymerase chain reaction - a systematic review
ReviewAbstract: Animal reservoirs contribute considerably to the dissemination of Trypanosoma cruzi, the etiologicalPalabras claves:Chagas disease, QPCR, Reservoirs, review, TRYPANOSOMA CRUZIAutores:Diogo Ventura Lovato, Gadelha F.R., Miguel D.C., Vitor Klipel da Silva BertoliniFuentes:scopusAn organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights
ArticleAbstract: Leishmaniasis is one of the most important neglected diseases, classically characterized by three clPalabras claves:Gold compound, LEISHMANIA, Murine cutaneous leishmaniasis, N-heterocyclic carbeneAutores:Angela Casini, Camilla Abbehausen, Consonni S.R., Gadelha F.R., Guillermo Moreno Alcántar, J. V. Fontes, Lizandra Maia de Sousa, Mariana Borges Costa Brioschi, Miguel D.C., Minori K., Riccardo BonsignoreFuentes:scopusIn Vitro and In Vivo Leishmanicidal Activity of Beauvericin
ArticleAbstract: Leishmaniasis is a worldwide disease caused by more than 20 species of Leishmania parasites. LeishmaPalabras claves:Autores:Andressa R. Biz, Felipe Hilário, Ferreira A.G., Gadelha F.R., Helder L. Teles, Juliana R. Gubiani, Marcelo R. de Amorim, Marcos A. Soares, Miguel D.C., Minori K., Roberto G.S. Berlinck, Virlânio A. de Oliveira Filho, Vitor Klipel da Silva Bertolini, Vitória D. BorgonoviFuentes:scopusExploring antiviral and antiparasitic activity of gold N-heterocyclic carbenes with thiolate ligands
ArticleAbstract: Gold(i) N-heterocyclic carbenes have been explored for their therapeutic potential against several dPalabras claves:Autores:Ana C.G. Jardim, Ana Laura C. Oliveira, Camilla Abbehausen, Gadelha F.R., Gustavo Clauss, Igor S. Oliveira, Jennyfer Castro, João Honorato, Lara C.F. Freitas, Marcus S.A. Garcia, Miguel D.C., Natasha M. Cassani, Vitor Klipel da Silva BertoliniFuentes:scopusOld Versus New Approaches Towards TriTryp Diseases
OtherAbstract: Neglected tropical diseasesNeglected tropical diseases represent a heavy burden for human civilizatiPalabras claves:Chagas disease, drugs, human African trypanosomiasis, leishmaniasis, neglected tropical diseasesAutores:Bruna Eduarda Siqueira da Silva, Camilla Abbehausen, Gadelha F.R., J. V. Fontes, Marcus S.A. Garcia, Miguel D.C.Fuentes:scopusAstaxanthin induces autophagy and apoptosis in murine melanoma B16F10-Nex2 cells and exhibits antitumor activity in vivo
ArticleAbstract: Countless efforts have been made to prevent and suppress the formation and spread of melanoma. NaturPalabras claves:Antitumor activity, apoptosis, Astaxanthin, Autophagy, cell migration, INVASION, melanoma, metastasisAutores:Agnes Kobayashi Calvo de Sant’ana, Angela Pedroso Tonon, Denise Costa Arruda, Fabricio Machado, Fernanda Fernandes Miranda da Cunha, Gadelha F.R., João Fernando Possatto, Luiz R. Travassos, Miguel D.C., Nathália Grazzia, Rayssa de Mello Lopes, Tiago RodriguesFuentes:scopusModels for cytotoxicity screening of antileishmanial drugs: what has been done so far?
ReviewAbstract: A growing number of studies have demonstrated the in vitro potential of an impressive number of antiPalabras claves:Antileishmanial assay, In vitro cytotoxicity, LEISHMANIA, macrophageAutores:Adriano C. Coelho, Elizabeth M. Coser, Gadelha F.R., Mariana Borges Costa Brioschi, Miguel D.C.Fuentes:scopusBiological characterization of Trypanosoma cruzi epimastigotes derived from trypomastigotes isolated from Brazilian chagasic patients
ArticleAbstract: Chagas disease (CD), caused by Trypanosoma cruzi, occurs in several countries in Latin America and nPalabras claves:Chagas disease, Mitochondrial bioenergetics, TRYPANOSOMA CRUZIAutores:Andressa Bruscato, De Almeida E.A., Dimas Campiolo, Eduardo de Figueiredo Peloso, Gadelha F.R., Isabella Bagni Nakamura, Mariane Barroso Pereira, Miguel D.C.Fuentes:scopus