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Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17β-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells
ArticleAbstract: Human 17β-hydroxysteroid dehydrogenase types 1 and 2 (17βHSD1 and 17βHSD2) regulate estrogen potencyPalabras claves:Autores:Akbar S., Guryev O.L., Mizrachi D., Papari-Zareei M., Rambally S., Richard J. Auchus, Sherbet D.P.Fuentes:scopus5α-androstane-3α,17β-diol is formed in tammar wallaby pouch young testes by a pathway involving 5α-pregnane-3α,17α-diol-20-one as a key intermediate
ArticleAbstract: The synthetic pathway by which 5α-androstane-3α,17β-diol (5α-adiol) is formed in the testes of tammaPalabras claves:Autores:Estabrook R.W., Guryev O.L., Leihy M.W., Osborn S.M., Renfree M.B., Richard J. Auchus, Shaw G., Wilson J.D.Fuentes:scopus5α-reduced C<inf>21</inf> steroids are substrates for human cytochrome P450c17
ArticleAbstract: The 5α-reduction of testosterone in target tissues is a key step in androgen physiology; however, 5αPalabras claves:17-hydroxylase/17,20-lyase, 3α-Hydroxysteroid dehydrogenase, 5α-reductase, Allopregnanolone, Androstanediol, CYP17, Cytochrome b 5, Dihydrotestosterone, P450c17, Sexual differentiationAutores:Gupta M.K., Guryev O.L., Richard J. AuchusFuentes:scopus