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Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
ArticleAbstract: Pyrin responds to pathogen signals and loss of cellular homeostasis by forming an inflammasome complPalabras claves:Autores:Amselem S., Baker P.J., Cochet E., Copin B., Dagley L.F., De Nardo D., De Somer L., Dooley J., Goris A., Holley C.L., Jeandel P.Y., Jéru I., Josselyn E. Garcia-Perez, Lagou V., Lawless D., Liston A., Lyras D., Masters S.L., Medlej-Hashim M., Megarbane A., Moghaddas F., Nicholson S.E., Parry D.A., Pasciuto E., Ruuth-Praz J., Savic S., Schroder K., Sciot R., Van Eyck L., Van Nieuwenhove E., Webb A.I., Wouters C.H.Fuentes:scopusGenetic Architecture of Adaptive Immune System Identifies Key Immune Regulators
ArticleAbstract: The immune system is highly diverse, but characterization of its genetic architecture has lagged behPalabras claves:adaptive immune system, association, autoimmunity, Genetics, Genome-wide association, immune phenotype, susceptibilityAutores:Boeckxstaens G., Bowness P., Chen L., Dooley J., Dubois B., Goris A., Hilven K., Humblet-Baron S., Josselyn E. Garcia-Perez, Lagou V., Liston A., Mallants K., Moisse M., Prezzemolo T., Smets I., Van Damme P., Van Horebeek L., Vandebergh M.Fuentes:scopus