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A novel phospholipase A2 (D49) from the venom of the Crotalus oreganus abyssus (North American Grand Canyon rattlesnake)
ArticleAbstract: Currently, Crotalus viridis was divided into two species: Crotalus viridis and Crotalus oreganus. ThPalabras claves:Autores:Acosta G.A., Alberício F., Baldasso P.A., Caballol M.A.O., Carvalho B.M.A., de Azevedo Calderon L., Honório K.M., Maltarollo V.G., Marangoni S., Martins W., Oliveira E., Ribeiro R.I.M.A., Saulo L. Silva, Soares A.M., Stábeli R.G., W. MartinsFuentes:scopusSnake venom L-amino acid oxidases: Trends in pharmacology and biochemistry
ReviewAbstract: L-amino acid oxidases are enzymes found in several organisms, including venoms of snakes, where theyPalabras claves:Autores:Costa T.R., de Azevedo Calderon L., Fernandes C.F.C., Grabner A.N., Izidoro L.F.M., Mendes M.M., Rodrigues V.M., Saulo L. Silva, Soares A.M., Sobrinho J.C., Stábeli R.G., Zanchi F.B., Zuliani J.P.Fuentes:scopusSnake venom, a natural library of new potential therapeutic molecules: Challenges and current perspectives
ReviewAbstract: Background: Research involving snake venom has gradually surpassed the simple discovery of new molecPalabras claves:Biotechnological applications, New therapeutics, Protein purification, Snake venoms, Toxins, venomicsAutores:Alfonso J.J., Gómez A.F., Grabner F.P., Holanda R.J., Jose Rafael de Almeida, Kayano A.M., Moreira-Dill L.S., Saulo L. Silva, Simões-Silva R., Soares A.M., Sobrinho J.C., Stábeli R.G., Zaqueo K.D., Zuliani J.P.Fuentes:googleorcidscopusStructural and functional characterization of a γ-type phospholipase A2 inhibitor from Bothrops jararacussu Snake Plasma
ArticleAbstract: Phospholipases A<inf>2</inf> (PLA<inf>2</inf>s) from snake venoms comprise a group of 14-18 kDa protPalabras claves:Biochemical characterization, Bothrops jararacussu, Snake venom, γ-type inhibitorAutores:Boldrini-França J., de Azevedo Calderon L., Giglio J.R., Menaldo D.L., Oliveira C.Z., Rodrigues F.H.S., Santos-Filho N.A., Saulo L. Silva, Soares A.M., Stábeli R.G., Tasic L.Fuentes:scopusStructural, enzymatic and pharmacological profiles of AplTX-II - A basic sPLA2 (D49) isolated from the Agkistrodon piscivorus leucostoma snake venom
ArticleAbstract: A basic sPLA<inf>2</inf> (D49) from the venom of snake Agkistrodon piscivorus leucostoma (AplTX-II)Palabras claves:Agkistrodon piscivorus leuscostoma, Basic sPLA D49 2, Basic sPLA2 D49, molecular modeling, NOBA (4-nitro-3-octanoyloxy benzoic acid)Autores:Fernandes P.A., Jose Rafael de Almeida, Marangoni S., Ramos M.J., Resende L.M., Saulo L. Silva, Soares A.M., Tatiana A. Guaraca-Medina, Viegas M.F.Fuentes:googleorcidscopusSynergism of in vitro plasmodicidal activity of phospholipase A2 isoforms isolated from panamanian Bothrops asper venom
ArticleAbstract: Bothrops asper is one of the most important snake species in Central America, mainly because of itsPalabras claves:antiparasitic activity, Bothrops asper, Phospholipases A 2, Phospholipases A2, Snake venom, synergismAutores:Alfonso J.J., Celeste Vega Gómez, de Medeiros D.S.S., Fuly A.L., Gómez A.F., Gómez C.V., Kayano A.M., Pereira S.S., Quintero A., Saulo L. Silva, Simões-Silva R., Soares A.M., Sobrinho J.C., Stábeli R.G., Teles C.B.G.Fuentes:scopusSynthesis and evaluation of sesquiterpene lactone inhibitors of phospholipase A2 from Bothrops jararacussu
ArticleAbstract: Several sesquiterpene lactone were synthesized and their inhibitive activities on phospholipase A<inPalabras claves:Bothrops jararacussu, Chemometrics, DFT, PLA2, Sesquiterpene lactoneAutores:Barosa L.C.A., de Alvarenga E.S., Demuner A.J., Ferreira J.M.S., Granjeiro P.A., Marangoni S., Marcussi S., Parreira A.G., Resende R.R., Ribeiro R.I.M.A., Saulo L. Silva, Silva J.A., Silva S.A., Soares A.M.Fuentes:scopusThe chemistry of snake venom and its medicinal potential
ReviewAbstract: The fascination and fear of snakes dates back to time immemorial, with the first scientific treatisePalabras claves:Autores:Ana L. Oliveira, Fernandes P.A., Oliveira A.L., Ramos M.J., Saulo L. Silva, Soares A.M., Viegas M.F.Fuentes:scopusSnake venom PLA2s inhibitors isolated from Brazilian plants: synthetic and natural molecules
ArticleAbstract: Ophidian envenomation is an important health problem in Brazil and other South American countries. IPalabras claves:Autores:Carvalho B.M.A., de Azevedo Calderon L., Jose Rafael de Almeida, Marangoni S., Marchi-Salvador D.P., Marcussi S., Martins W., Resende L.M., Santos J.D.L., Saulo L. Silva, Soares A.M., Stábeli R.G., W. Martins, Xavier B.M.Fuentes:googleorcidscopusSnake Venom Peptides and Low Mass Proteins: Molecular Tools and Therapeutic Agents
ArticleAbstract: Snake venoms are natural sources of biologically active molecules that are able to act selectively aPalabras claves:Bradykinin-potentiating peptide, Crotamine, Disintegrin, Natriuretic peptide, Sarafotoxin, Three-finger toxinAutores:Caldeira C.A.S., Carregari V.C., Coutinho-Neto A., de Azevedo Calderon L., Gomes P.A.D.C., Huancahuire-Vega S., Jose Rafael de Almeida, Marangoni S., R. K. Watanabe, Resende L.M., Saulo L. Silva, Soares A.M., Valed N.Fuentes:googleorcidscopus