Documentos de Pessoa-Mahana H. | REDI

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Scientific Reports(1)

Toxicology and Applied Pharmacology(1)

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Enfermedades(2)

Farmacología y terapéutica(1)

Fisiología y materias afines(1)

Microorganismos, hongos y algas(1)

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Palabras Claves

Anti-cancer agents(1)

Hydroquinones(1)

Oxidative phosphorylation(1)

FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway

Abstract: Highly malignant triple-negative breast cancer (TNBC) cells rely mostly on glycolysis to maintain ce

Palabras claves:

Ahumada-Castro U., Araya-Maturana R., Bustos G., Cárdenas C., Córdova-Delgado M., Cruz P., Ferreira J., Millas-Vargas J.P., Morales D., Muñoz F., Oney O. Ramírez-Rodríguez, Pavani M., Peña-Ahumada B., Pessoa-Mahana H., Pulgar R., Ramírez M.P., Retamal E., Rios M., Silva-Pavez E., Urra F.A., Varela D.

Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation

Abstract: Mitochondria participate in several distinctiveness of cancer cell, being a promising target for the

Palabras claves:

Anti-cancer agents, Complex I, Hydroquinones, Oxidative phosphorylation, Uncouplers

Acevedo-Arévalo L., Andrea Orellana Manzano, Araya-Maturana R., Córdova-Delgado M., Ferreira J., González-Vivanco J.M., Lapier M., Martínez-Cifuentes M., Millas-Vargas J.P., Oney O. Ramírez-Rodríguez, Pavani M., Pessoa-Mahana H., Urra F.A., Weiss-López B.