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Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase
ArticleAbstract: Hypoxia-inducible factors (HIF) are heterodimeric (α/β) transcription factors that play a fundamentaPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Castellanos M.C., Feijóo-Cuaresma M., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Temes E.Fuentes:scopusDown-regulation of hypoxia-inducible factor-2 in PC12 cells by nerve growth factor stimulation
ArticleAbstract: Cellular responses to low oxygen tension are mediated, at least in part, by the activation of the hyPalabras claves:Autores:Álvarez-Tejado M., Castellanos M.C., Manuel Ortiz de Landázuri, Naranjo-Suárez S., Peso L.D., Vara A.Fuentes:scopusInadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells
ArticleAbstract: The von Hippel-Lindau (VHL) tumor suppressor gene regulates extracellular matrix deposition. In VHLPalabras claves:Autores:Calzada M.J., Castellanos M.C., Del Cerro M.H., Esteban M.A., Feijóo-Cuaresma M., García‐Pardo A., Manuel Ortiz de Landázuri, Maqueda A., Méndez F., Naranjo-Suárez S., Vazquez S.N.Fuentes:scopusTranscriptional Up-Regulation of Intracellular Adhesion Molecule-1 in Human Endothelial Cells by the Antioxidant Pyrrolidine Dithiocarbamate Involves the Activation of Activating Protein-1
ArticleAbstract: The redox status of the cell plays an essential role in regulating signal transduction, transcriptioPalabras claves:Autores:Alfranca A., Castellanos M.C., Esteban M.A., Manuel Ortiz de Landázuri, Muñoz C., Redondo J.M., Vara A.Fuentes:scopusVon Hippel-Lindau tumor suppressor protein regulates the assembly of intercellular junctions in renal cancer cells through hypoxia-inducible factor-independent mechanisms
ArticleAbstract: Inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene is responsible for the developmentPalabras claves:Autores:Calzada M.J., Castellanos M.C., Esteban M.A., Feijóo-Cuaresma M., Manuel Ortiz de Landázuri, Méndez F., Naranjo-Suárez S., Ohh M., Temes E., Yáñez-Mó M.Fuentes:scopusSpecific Oncolytic Effect of a New Hypoxia-Inducible Factor-Dependent Replicative Adenovirus on von Hippel-Lindau-Defective Renal Cell Carcinomas
ArticleAbstract: Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene are responsible for a hebkp_reditaryPalabras claves:Autores:Aragonés J., Castellanos M.C., Cuevas Y., Esteban M.A., Hernández-Alcoceba R., Manuel Ortiz de Landázuri, Martin-Puig S., Naranjo-Suárez S., Peso L.D.Fuentes:scopusThe von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen
ArticleAbstract: Most of the genes induced by hypoxia are regulated by a family of transcription factors termed hypoxPalabras claves:Autores:Castellanos M.C., Cuevas Y., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Peso L.D., Temes E.Fuentes:scopus