Documentos de Shimshek D.R. | REDI

Regresar

Mostrando 1 resultados de: 1

Filtros aplicados

Palabras Claves: "Glucocerebrosidase"

Subtipo de publicación

Publisher

Neurobiology of Disease(1)

Área temáticas

Enfermedades(1)

Fisiología humana(1)

Sistemas fisiológicos específicos de los animales(1)

Área de conocimiento

Año de Publicación

Origen

Palabras Claves

Chaperone-mediated autophagy(1)

G2019S LRRK2(1)

Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo

Abstract: Mutations in leucine-rich repeat kinase 2 (LRRK2) are associated with Parkinson's disease. LRRK2 mod

Palabras claves:

Autophagy, Chaperone-mediated autophagy, Chloroquine, G2019S LRRK2, Glucocerebrosidase, LC3, MLi-2, Parkinson's Disease, pSer129 α-synuclein, TFEB

Albanese F., Finetti L., Giovanni Bernacchia, Lamonaca G., Mercatelli D., Morari M., Pizzi S., Shimshek D.R.