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A new method for determining blood-brain barrier integrity based on intracardiac perfusion of an Evans Blue-Hoechst cocktail
ArticleAbstract: A new method for determining brain regions with blood-brain barrier (BBB) alterations is described.Palabras claves:blood-brain barrier, Cryoinjury, Evans blue, Fluorescence, Hoechst, Immunohistochemistry, tracersAutores:Antoni Camins, Del Valle J., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusExpression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid
ArticleAbstract: 3-Nitropropionic acid (3-NPA) is a mitochondrial toxin used in the laboratory to replicate neurodegePalabras claves:Immunohistochemistry, Neurotoxin, RATAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusNeuronal apoptosis in the striatum of rats treated with 3-nitropropionic acid is not triggered by cell-cycle re-entry
ArticleAbstract: Although terminally differentiated neurons lack the capacity to undergo cell division, they retain tPalabras claves:3-nitropropionic acid, apoptosis, Cell-cycle re-entry, Immunohistochemistry, NeurodegenerationAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusIncreased permeability of blood-brain barrier on the hippocampus of a murine model of senescence
ArticleAbstract: SAMP8 mice show several indicative characteristics of accelerated aging and have been used to studyPalabras claves:blood-brain barrier, Confocal microscopy, hippocampus, IgG quantification, Immunohistochemistry, mouse, SAMP8, SenescenceAutores:Antoni Camins, Canudas A.M., Casadesús G., Del Valle J., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopusRole of matrix metalloproteinase-9 (MMP-9) in striatal blood-brain barrier disruption in a 3-nitropropionic acid model of Huntington's disease
ArticleAbstract: Aim: 3-Nitropropionic acid (3-NPA) is a natural toxin that, when administered to experimental animalPalabras claves:3-nitropropionic acid, blood-brain barrier, Huntington's disease, Immunohistochemistry, Matrix metallopro teinase, StriatumAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopus