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Pharmaceuticals(3)
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scopus(6)
2017 FDA peptide harvest
ReviewAbstract: 2017 was an excellent year in terms of new drugs (chemical entities and biologics) approved by the FPalabras claves:Drug Discovery, drugs, Pharmaceutical market, Solid-phase peptide synthesisAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopus2018 FDA Tides Harvest
ReviewAbstract: In 2018, the United States Food and Drug Administration (FDA) approved a total of 59 new drugs, threPalabras claves:Dotatate, drugs, Inotersen, Lutathera, Oligonucleotides, Onpattro, Patisiran, Peptides, Pharmaceutical market, TegsediAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopus2022 FDA TIDES (Peptides and Oligonucleotides) Harvest
ArticleAbstract: A total of 37 new drug entities were approved in 2022; although that year registered the lowest numbPalabras claves:drugs, FDA, gadopiclenol, lutetium ( Lu) vipivotide tetraxetan 177, Oligonucleotides, Peptides, terlipressin, tirzepatide, vutrisiranAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopusHydroxamate siderophores: Natural occurrence, chemical synthesis, iron binding affinity and use as Trojan horses against pathogens
ReviewAbstract: Hydroxamic acids are an important class of molecules, in particular because of their metal-chelatingPalabras claves:Fe (III) binding affinity, Hydroxamate, Sideromycins, Siderophore, Siderophore-drug conjugate, Trojan horseAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopusSolid-phase synthesis of peptides containing 1-Hydroxypyridine-2-one (1,2-HOPO)
ArticleAbstract: Herein a friendly method for the preparation of 1-hydroxypyridine-2-one (1,2-HOPO)-containing peptidPalabras claves:Bzl protecting group, Fe(III) chelating compounds, Siderophores, Solid-phase peptide synthesis, Trifluoromethanesulfonic acidAutores:Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopusSynthesis of New Peptide-Based Ligands with 1,2-HOPO Pendant Chelators and Thermodynamic Evaluation of Their Iron(III) Complexes**
ArticleAbstract: Hydroxypyridones (HOPOs) are an important class of chelating compounds. They bind strongly to hard mPalabras claves:Chelation, constants, Peptides, Protonation constants, Siderophore, stabilityAutores:Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopus