Mostrando 5 resultados de: 5
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British Journal of Pharmacology(3)
Naunyn-Schmiedeberg's Archives of Pharmacology(1)
Pharmacology and Therapeutics(1)
Assessing the (a)symmetry of concentration-effect curves: Empirical versus mechanistic models
ReviewAbstract: Modeling the shape of concentration-effect curves is of prime importance in pharmacology. GeometricPalabras claves:asymmetry, Curve fitting, G-protein-coupled receptors, Ionic channels, Receptor reserve, Slope parameterAutores:Badia A., Elisabet Vila, Giraldo J., Vivas N.M.Fuentes:scopusEndothelial modulation of α<inf>1</inf>-adrenoceptor contractile responses in the tail artery of spontaneously hypertensive rats
ArticleAbstract: 1. Vascular contraction induced by phenylephrine was studied in tail artery rings from spontaneouslyPalabras claves:endothelium, Hypertension, Tail artery, [ H]-prazosin binding 3, α -Adrenoceptors 1Autores:Badia A., Elisabet Vila, Giraldo J., Tabernero A., Vivas N.M.Fuentes:scopusUse of the operational model of agonism and [<sup>3</sup>H]prazosin binding to assess altered responsiveness of α<inf>1</inf>-adrenoceptors in the vas deferens of spontaneously hypertensive rat
ArticleAbstract: Changes in functional responsiveness to α1-adrenoceptor activation with noradrenaline and in [3H]praPalabras claves:Agonist affinity, Agonist efficacy, Hypertension, Operational model, Vas deferens, [ H]Prazosin binding 3, α -Adrenoceptors 1Autores:Badia A., Elisabet Vila, Giraldo J., Tabernero A., Vivas N.M.Fuentes:scopusα<inf>1</inf>-adrenoceptor vasoconstriction in the tail artery during ageing
ArticleAbstract: 1. We have studied the α1-adrenoceptor-mediated responses in intact tail artery rings from 3-4 and 2Palabras claves:ageing, endothelium, Tail artery, α -adrenoceptor responsiveness 1Autores:Arribas S.M., Elisabet Vila, Giraldo J., Tabernero A., Vivas N.M.Fuentes:scopusSources of calcium and α<inf>1</inf>-adrenoceptor-mediated contraction in rat tail artery
ArticleAbstract: 1. The relative importance of intracellular and extracellular Ca2+ on α1-adrenoceptor mediated contrPalabras claves:Calcium antagonist, Phosphoinositide hydrolysis, Tail artery, [ H]-prazosin binding 3, α -Adrenoceptors 1Autores:Elisabet Vila, Tabernero A., Vivas N.M.Fuentes:scopus