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Stroke(2)
International Journal of Stroke(1)
JAMA Neurology(1)
Journal of Hypertension(1)
New England Journal of Medicine(1)
Comparative effects of intensive-blood pressure versus standard-blood pressure-lowering treatment in patients with severe ischemic stroke inthe ENCHANTEDtrial
ArticleAbstract: Objective: Limited data exist on the optimum level of SBP in thrombolyzed patients with acute ischemPalabras claves:Hypertension, Ischemic stroke, large vessel occlusion, recanalization, thrombolysis, TrialAutores:Anderson C.S., Bath P.M.W., Broderick J.P., Chalmers J., Delcourt C., Demchuk A.M., Durham A.C., Kim J.S., Lavados P.M., Lee T.H., Lindley R.I., Martins S.O., Minhas J.S., Octavio Marques Pontes-Neto, Ricci S., Robinson T.G., Sharma V.K., Song L., Wang J.G., Wang X., Woodward M.Fuentes:scopusAssociations of Early Systolic Blood Pressure Control and Outcome after Thrombolysis-Eligible Acute Ischemic Stroke: Results from the ENCHANTED Study
ArticleAbstract: Background and Purpose: In thrombolysis-eligible patients with acute ischemic stroke, there is uncerPalabras claves:Blood pressure, Hypertension, intracranial hemorrhage, Ischemic strokeAutores:Anderson C.S., Arima H., Bath P.M.W., Broderick J.P., Chalmers J., Chen G., Chen X., Delcourt C., Demchuk A.M., Donnan G.A., Durham A.C., Lavados P.M., Lee T.H., Levi C., Lindley R.I., Luca Di Tanna G., Martins S.O., Minhas J.S., Moullaali T.J., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., Sato S., Sharma V.K., Silva-Sieger F.A., Song L., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopusEffects of intensive blood pressure lowering on cerebral ischaemia in thrombolysed patients: insights from the ENCHANTED trial
ArticleAbstract: Background: Intensive blood pressure lowering may adversely affect evolving cerebral ischaemia. We aPalabras claves:Acute ischaemic stroke, Blood pressure, Brain imaging, Cerebral infarction, Clinical trial, thrombolysisAutores:Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Chen C., Chen X., Delcourt C., Demchuk A.M., Donnan G.A., Lavados P.M., Levi C., Li G., Li Q., Lindley R.I., Liu L., Mair G., Martins S.O., Octavio Marques Pontes-Neto, Olavarria V.V., Ong S., Ouyang M., Parsons M.W., Robinson T.G., S Anderson C., Song L., Venturelli P.M., Wang X., Wardlaw J.M., Zhang G., Zhang L.Fuentes:scopusLow-Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy the ENCHANTED Trial (Enhanced Control of Hypertension and Thrombolysis Stroke Study)
Conference ObjectAbstract: Background and Purpose'Many patients receiving thrombolysis for acute ischemic stroke are on prior aPalabras claves:aspirin, Brain Infarction, Hypertension, intracranial hemorrhages, Tissue plasminogen activatorAutores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Demchuk A.M., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sato S., Sharma V.K., Wang J.G., Wang X., Woodward M.Fuentes:scopusLow-dose versus standard-dose intravenous alteplase in acute ischemic stroke
ArticleAbstract: BACKGROUND: Thrombolytic therapy for acute ischemic stroke with a lower-than-standard dose of intravPalabras claves:Autores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Cao Y., Chalmers J., Chen G., Chen X., Demchuk A.M., Donnan G.A., Huang Y., Kim J.S., Lavados P.M., Lee T.H., Levi C., Li Q., Lindley R.I., Martins S.O., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., Roffe C., S Anderson C., Sharma V.K., Silva-Sieger F.A., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopusLow-dose vs standard-dose alteplase for patients with acute ischemic stroke: Secondary analysis of the ENCHANTED randomized clinical trial
ArticleAbstract: IMPORTANCE: A lower dose of intravenous alteplase appears to be a safer treatment option than the stPalabras claves:Autores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Demchuk A.M., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Li Q., Lindley R.I., Martins S.O., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sharma V.K., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopusIntensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial
ArticleAbstract: Background: Systolic blood pressure of more than 185 mm Hg is a contraindication to thrombolytic trePalabras claves:Autores:Arima H., Armenis M., Bai X., Baig M.A., Bath P.M.W., Benito D., Billot L., Blacklock N., Bousser M.G., Broderick J.P., Cao Y., Carcel C., Chalmers J., Chen G., Chen R., Chen X., Cong Y., Coutts S., Cui B., Delcourt C., Demchuk A.M., Deng H., Donnan G.A., Donnelly P., Durham A.C., Fuentes-Patarroyo S.X., Glass P., Gordon P., Guo Y., Hankey G.J., Haunton V., He R., Hirakawa Y., Huang Y., Ivanova E., Jenson K., Jia H., Kim J.S., Knight E., Kong L., Kumar N.N., Kunchok A., Lavados P.M., Levi C., Li Q., Lim J.Y., Lindley R.I., Liu L., Lv J., Malavera A., Manning L., Martins S.O., Minhas J.S., Mistri A., Monaghan H., Moullaali T.J., Naidu B., Octavio Marques Pontes-Neto, Odgers E., Olavarria V.V., Parsons M.W., Ricci S., Richtering S., Robinson T.G., S Anderson C., Sandercock P., Sanders E., Sato S., Scaria A., Sharma V.K., Silva-Sieger F.A., Simes R.J., Small S., Smith P., Song L., Stapf C., Tay N., Thang N.H., Thembani E., Tucker S., Vaghasiya R., Wang J.G., Wang X., Wardlaw J.M., Winters S., Wong K.S.L., Woodward M., Wu G., Xi Z., Yang J., Yoshimura S., You S., Zhang S., Zhao H., Zhu P.Fuentes:scopusRationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2×2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment
ArticleAbstract: Rationale: Controversy exists over the optimal dose of intravenous (iv) recombinant tissue plasminogPalabras claves:Acute ischaemic stroke, Alteplase, Dose, Hypertension, Rt-PA, thrombolysisAutores:Arima H., Bath P.M.W., Broderick J.P., Chalmers J., Chen X., Demchuk A.M., Donnan G.A., Fuentes S., Huang Y., Kim J.S., Lavados P.M., Lee T.H., Levi C., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sharma V.K., Silva-Sieger F.A., Stapf C., Wang J.G., Woodward M.Fuentes:scopus