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Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children
ArticleAbstract: Deficiency of matrix metalloproteinase 2 (MMP-2) causes a complex syndrome characterized by multicenPalabras claves:cortisol, cytokines, Matrix metalloproteinase, matrix metalloproteinase-2, multicentric osteolysis nodulosis and arthropathyAutores:Botto L.D., Eugenio Hardy, Fernandez‐Patron C., Haimour A., Karim M.A., Martignetti J.A., Sarker H., Scholl-Bürgi S.Fuentes:scopusCould Endogenous Glucocorticoids Influence SARS-CoV-2 Infectivity?
ArticleAbstract: Endogenous glucocorticoids and their synthetic analogues, such as dexamethasone, stimulate receptor-Palabras claves:ACE2 (angiotensin converting enzyme 2), cortisol, covid-19, Dexamethasone, glucocorticoids, innate immunity, SARS-COV-2, Spike proteinAutores:Eugenio Hardy, Fernandez‐Patron C.Fuentes:scopusGlucocorticoids Bind to SARS-CoV-2 S1 at Multiple Sites Causing Cooperative Inhibition of SARS-CoV-2 S1 Interaction With ACE2
ArticleAbstract: Dexamethasone may reduce mortality in COVID-19 patients. Whether dexamethasone or endogenous glucocoPalabras claves:ACE2 (angiotensin converting enzyme 2), CORONAVIRUS, covid, glucocorticoids, innate immunity, SARS-COV-2Autores:Elahi S., Eugenio Hardy, Fernandez‐Patron C., Glover J.N.M., Panigrahi R., Sarker H.Fuentes:scopusEmerging pathways of communication between the heart and non-cardiac organs
ArticleAbstract: The breakthrough discovery of cardiac natriuretic peptides provided the first direct demonstration oPalabras claves:heart, inflammation, Liver, Matrix metalloproteinase, metabolism, microRNA, Natriuretic peptidesAutores:Eugenio Hardy, Fernandez‐Patron C.Fuentes:scopusIdentification of fibrinogen as a natural inhibitor of MMP-2
ArticleAbstract: Non-genetic MMP-2 insufficiency is a relatively unexplored condition which could be induced by pathoPalabras claves:Autores:Botto L.D., Eugenio Hardy, Fernandez‐Patron C., Haimour A., Maksymowych W.P., Sarker H.Fuentes:scopusTargeting mmp-regulation of inflammation to increase metabolic tolerance to covid-19 pathologies: A hypothesis
ArticleAbstract: Many individuals infected with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) devePalabras claves:AMPK, covid-19, inflammation, Meta-bolism, Metabolic tolerance, MMP, Pathogen, SARS-COV-2Autores:Eugenio Hardy, Fernandez‐Patron C.Fuentes:scopusMMP-2: Is too low as bad as too high in the cardiovascular system?
ReviewAbstract: Matrix metalloproteinase (MMP)-2 cleaves a broad spectrum of substrates, including extracellular matPalabras claves:heart, inflammation, Matrix metalloproteinase, metabolismAutores:Eugenio Hardy, Fernandez‐Patron C., Hardy-Sosa A.Fuentes:scopusMatrix Metalloproteinases in Health and Disease in the Times of COVID-19
OtherAbstract:Palabras claves:Autores:Eugenio Hardy, Fernandez‐Patron C.Fuentes:scopus