Mostrando 8 resultados de: 8
Filtros aplicados
Publisher
Journal of Clinical Endocrinology and Metabolism(3)
Cytochrome P450: Structure, Mechanism, and Biochemistry, Fourth Edition(1)
Endocrinology(1)
Endocrinology: Adult and Pediatric(1)
Journal of Biological Chemistry(1)
Área temáticas
Farmacología y terapéutica(5)
Fisiología humana(2)
Enfermedades(1)
Fisiología y materias afines(1)
Genética y evolución(1)
Origen
scopus(8)
Cytochrome b<inf>5</inf> augments the 17,20-lyase activity of human P450c17 without direct electron transfer
ArticleAbstract: In the biosynthesis of steroid hormones, P450c17 is the single enzyme that catalyzes both the 17α-hyPalabras claves:Autores:Lee T.C., Miller W.L., Richard J. AuchusFuentes:scopusMolecular evolution of adrenarche: Structural and functional analysis of P450c17 from four rimate species
ArticleAbstract: Adrenarche is the prepubertal onset of increased adrenal secretion of 19-carbon steroids, especiallyPalabras claves:Autores:Arlt W., Martens J.W.M., Miller W.L., Richard J. Auchus, Song M., Wang J.Fuentes:scopusP450 enzymes in steroid processing
Book PartAbstract: Steroid hormones are a group of biomolecules with similar structures derived from the common four-riPalabras claves:Autores:Miller W.L., Richard J. AuchusFuentes:scopusP450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b<inf>5</inf>
ArticleAbstract: Cytochrome P450c17 catalyzes steroid 17α-hydroxylase and 17,20-lyase activities and hence is a key ePalabras claves:Autores:Geller D.H., Miller W.L., Richard J. AuchusFuentes:scopusMedroxyprogesterone acetate and dexamethasone are competitive inhibitors of different human steroidogenic enzymes
ArticleAbstract: Medroxyprogesterone acetate (MPA), a widely used progestin, can suppress the hypothalamic-pituitary-Palabras claves:Autores:Lee T.C., Miller W.L., Richard J. AuchusFuentes:scopusRole of cytochrome b<inf>5</inf> in the 17,20-lyase activity of P450c17 [3]
OtherAbstract:Palabras claves:Autores:Miller W.L., Richard J. AuchusFuentes:scopusThe 17, 20-lyase activity of cytochrome P450c17 from human fetal testis favors the Δ<sup>5</sup> steroidogenic pathway
ArticleAbstract: Cytochrome P450c17 catalyzes both 17α-hydroxylation and 17,20-lyase conversion of 21-carbon steroidsPalabras claves:Autores:Flück C.E., Miller W.L., Richard J. AuchusFuentes:scopusThe Principles, Enzymes, and Pathways of Human Steroidogenesis
Book PartAbstract:Palabras claves:Autores:Miller W.L., Richard J. AuchusFuentes:scopus