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Fragment-Hopping-Based Discovery of a Novel Chemical Series of Proto-Oncogene PIM-1 Kinase Inhibitors
ArticleAbstract: A new chemical series, triazolo[4,5-b]pyridines, has been identified as an inhibitor of PIM-1 by a cPalabras claves:Autores:Albarran M.I., Alvarez R.M., Antonio Salgado, Bischoff J.R., Blanco C., Kurz G., Ortega M.A., Oyarzabal J., Pastor J., Pevarello P., Rabal O., Saluste G.Fuentes:scopusDiscovery of mitogen-activated protein kinase-interacting kinase 1 inhibitors by a comprehensive fragment-oriented virtual screening approach
ArticleAbstract: Mitogen-activated protein kinase-interacting kinases 1 and 2 (MNK1 and MNK2) phosphorylate the oncogPalabras claves:Autores:Albarran M.I., Antonio Salgado, Bischoff J.R., Corrionero A., Fominaya J., Mateos G., Oyarzabal J., Palacios I., Pastor J., Rabal O., Reymundo I., Urbano-Cuadrado M., Zarich N.Fuentes:scopus