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CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
ArticleAbstract: Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, wPalabras claves:apoptosis, Cancer targeted therapy, Casein kinase 2Autores:Acevedo B.E., Alonso D.F., Ariosa J., Bacardí D.M., Baladron I., Besada-Pérez V., Betancourt L., Castellanos L.R., Cosme K., Cruz M., Díaz A., Falcón-Cama V., Farina H., Garay H.E., Gil J., Gómez D., Gómez R., González L.J., Hernández I., Herrera L., López C., López-Mola E., López-Saura P.A., Marcelo J.L., Mendoza O., Perea-Rodríguez S.E., Perera Y., Puchades Y., Reyes O., Rodriguez A., Sánchez A., Santana A., Serrano J.M., Sigman H., Silva R., Solares M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusPhycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats
ArticleAbstract: Since the inflammatory response and oxidative stress are involved in the stroke cascade, we evaluatePalabras claves:Cerebral hypoperfusion, Gene Expression, inflammation, Oxidative Stress, PC12, phycocyanobilinAutores:Alexey Llópiz-Arzuaga, Cintado-Benítez A., Cruz-Ramírez A., Fernández-Massó J.R., Marín-Prida J., Mendoza-Marí Y., Nazabal-Galvez M., Pardo-Andreu G.L., Pavón-Fuentes N., Pentón-Arias E., Pentón-Rol G., Polentarutti N., Riva F., Roche L.D., Santana S.P., Valenzuela-Silva C.M.Fuentes:googlescopus