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Clinical Pharmacology and Therapeutics(2)
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scopus(5)
Assessment of the debrisoquin and dextromethorphan phenotyping tests by gaussian mixture distributions analysis
ArticleAbstract: From a sample of 149 unrelated Spaniards, individuals were phenotyped for their ability to hydroxylaPalabras claves:Autores:Adrián LLerena, Avram M., Benitez Rodriguez J., C. Martinez, Cobaleda J., Gibbons R., Henthorn T., Krejcie T., Martinez C.Fuentes:scopusInterethnic differences in drug metabolism: Influence of genetic and environmental factors on debrisoquine hydroxylation phenotype
Conference ObjectAbstract: Genetic and environmental factors are determinants of the interindividual and interethnic variabilitPalabras claves:CYP2D6, debrisoquine, gender, pharmacogenetics, smokingAutores:Adrián LLerena, Benitez Rodriguez J., Cobaleda J., Martínez C.Fuentes:scopusInfluence of genetic admixture on polymorphisms of drug-metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic population
ArticleAbstract: Objectives and study design: The genetic basis of two polymorphisms of drug- and carcinogen-metaboliPalabras claves:Autores:Adrián LLerena, Agúndez J.A.G., Benitez Rodriguez J., Hernandez M., Martínez C., Olivera M., Ramirez R.Fuentes:scopusMolecular heterogeneity at the CYP2D gene locus in Nicaraguans: Impact of gene-flow from Europe
ArticleAbstract:Palabras claves:CYP2D, Cytochrome p450, gene flow, Hispanics, NicaraguansAutores:Adrián LLerena, Agúndez J.A.G., Benitez Rodriguez J., Hernandez M., Ramirez R.Fuentes:scopusPolymorphic oxidation of debrisoquine in bladder cancer
ArticleAbstract: The oxidative polymorphism of debrisoquine has been determined in 125 patients with bladder cancer aPalabras claves:bladder cancer, debrisoquine, OXIDATION, polymorphismAutores:Adrián LLerena, Aurelio C. Uson, Benitez Rodriguez J., Cobaleda J., Fernandez-Gundin M.J., Fidel González-Rozas, Jesús Rodríguez-Molina, Juan Prados, Ladero J.M., Martínez C., Muñoz J.J., Vargas E.Fuentes:scopus