Mostrando 4 resultados de: 4
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Acta Psychiatrica Scandinavica(1)
European Journal of Clinical Pharmacology(1)
European Journal of Drug Metabolism and Pharmacokinetics(1)
Therapeutic Drug Monitoring(1)
Área temáticas
Fisiología humana(3)
Enfermedades(2)
Farmacología y terapéutica(2)
Bioquímica(1)
Medicina y salud(1)
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scopus(4)
Frequency of S-mephenytoin hydroxylation deficiency in 373 spanish subjects compared to other Caucasian populations
ArticleAbstract: We have investigated the prevalence of poor metabolisers (PM) of S-mephenytoin in 373 unrelated, heaPalabras claves:caucasian, drug metabolism, Mephenytoin, pharmacogenetics, Phenotype, polymorphismAutores:Adrián LLerena, Benitez Rodriguez J., Bertilsson L., Carrillo J.A., Reviriego J., Valdivielso M.J.Fuentes:scopusInterethnic differences in drug metabolism: Influence of genetic and environmental factors on debrisoquine hydroxylation phenotype
Conference ObjectAbstract: Genetic and environmental factors are determinants of the interindividual and interethnic variabilitPalabras claves:CYP2D6, debrisoquine, gender, pharmacogenetics, smokingAutores:Adrián LLerena, Benitez Rodriguez J., Cobaleda J., Martínez C.Fuentes:scopusUse of the mesoridazine/thioridazine ratio as a marker for CYP2D6 enzyme activity
ArticleAbstract: Thioridazine is metabolized in humans by CYP2D6 to mesoridazine, which is an active metabolite. TwoPalabras claves:CYP2D6, High-pressure liquid chromatography, pharmacogenetics, Therapeutic drug monitoring (TDM), ThioridazineAutores:Adrián LLerena, Benitez Rodriguez J., Berecz R., De la Rubia A., Norberto M.Fuentes:scopusRelationship between personality and debrisoquine hydroxylation capacity: Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6
ArticleAbstract: We administered the Karolinska Scales of Personality to 225 healthy subjects in Spain selected fromPalabras claves:debrisoquine, personality, pharmacogeneticsAutores:Adrián LLerena, Benitez Rodriguez J., Bertilsson L., Cobaleda J., Edman G., Schalling D.Fuentes:scopus