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Biotecnologia Aplicada(3)
FEBS Letters(1)
Journal of Pharmaceutical and Biomedical Analysis(1)
Molecular and Cellular Biochemistry(1)
Protein Engineering, Design and Selection(1)
Characterization of the primary structure of the recombinant human interleukin-2
ArticleAbstract:Palabras claves:Autores:Araña M.J., Besada-Pérez V., Castellanos L.R., López P., Mata H., Mateo de Acosta C., Richardson M., Vivian Morera CórdovaFuentes:scopusA modified variant of human Interleukin-15 as a novel antigen for active immunotherapy in rheumatoid arthritis
ReviewAbstract: Interleukin (IL)-15 is a pro-inflammatory cytokine that plays a crucial role in the pathogenesis ofPalabras claves:IL-15, Immunization, neutralizing antibodies, non-human primates, Rheumatoid ArthritisAutores:Alexey Llópiz-Arzuaga, Arrieta C.A., Besada-Pérez V., Castro-Velazco J., Eugenio Hardy, Geronimo H., Guillén-Nieto G.E., Martínez K., Martínez-Castillo R., Morera-Díaz Y., Moro A., Perea-Rodríguez S.E., Puente P., Ramos Y., Rodríguez-Álvarez Y., Santos-Savio A., Silva R., Vázquez M.Fuentes:scopusDevelopment and validation of a bioanalytical LC-MS method for the quantification of GHRP-6 in human plasma
ArticleAbstract: Growth hormone-releasing peptide 6 (GHRP-6, His-(DTrp)-Ala-Trp-(DPhe)-Lys-NH 2, MW=872.44Da) is a poPalabras claves:GHRP-6, internal standard, LC-MS, Method validation, PlasmaAutores:Besada-Pérez V., Betancourt L., Cabrales A., García G., Gil J., González L.J., Moya G., Padrón G., Reyes O., Sánchez A., Vivian Morera CórdovaFuentes:scopusCIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
ArticleAbstract: Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, wPalabras claves:apoptosis, Cancer targeted therapy, Casein kinase 2Autores:Acevedo B.E., Alonso D.F., Ariosa J., Bacardí D.M., Baladron I., Besada-Pérez V., Betancourt L., Castellanos L.R., Cosme K., Cruz M., Díaz A., Falcón-Cama V., Farina H., Garay H.E., Gil J., Gómez D., Gómez R., González L.J., Hernández I., Herrera L., López C., López-Mola E., López-Saura P.A., Marcelo J.L., Mendoza O., Perea-Rodríguez S.E., Perera Y., Puchades Y., Reyes O., Rodriguez A., Sánchez A., Santana A., Serrano J.M., Sigman H., Silva R., Solares M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusExpression and folding of an interleukin-2-proinsulin fusion protein and its conversion into insulin by a single step enzymatic removal of the C-peptide and the N-terminal fused sequence
ArticleAbstract: We report the expression in E. coli of a proinsulin fusion protein carrying a modified interleukin-2Palabras claves:Enzymatic processing, Proinsulin folding, Recombinant insulinAutores:Besada-Pérez V., Castellanos‐Serra L., Eugenio Hardy, Falcón-Cama V., Fernandez C., Gonzalez M., Herrera L., Perez G., Santiago Nelson Vispo, Santos-Savio A., Silva A., Ubieta R.Fuentes:scopusExpression of il-2/proinsulin fusion protein: Folding of the fusion protein and conversion into insulin by a one step removal of c-peptide and leader sequence
ArticleAbstract:Palabras claves:Autores:Besada-Pérez V., Castellanos L.R., Estrada R., Eugenio Hardy, Fernandez C., Gonzalez M., Herrera L., Jimenez V., Perez G., Santiago Nelson Vispo, Silva A., Ubieta R.Fuentes:scopusMolecular characterization of recombinant human interferon alpha-2b produced in Cuba
ArticleAbstract: The recombinant human interferon α 2b (IFN-γ(2b)) produced by Cuban technology is obtained from EschPalabras claves:IFN, Molecular characterization, Recombinant human interferon alfa 2bAutores:Beldarrain A., Besada-Pérez V., Betancourt L., Brito R., Curras T., Eugenio Hardy, Ferrero J., Gil M., González L.J., Herrera L., Huerta V., Martinez E., Moya G., Pujols V., Sanchez J.C., Santana-Milián H., Sosa R., Vivian Morera CórdovaFuentes:googlescopus