Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates

Article

Abstract: The cytochrome P450 family 1 enzymes (CYP1s) are a diverse family of hemoprotein monooxygenases, whi

Palabras claves:

ancestral sequence reconstruction, CYP1A2, CYP1B1, Cytochrome p450, drug metabolism, thermostability

Autores:

Andersson S., Boden M., Foley G., Gillam E.M.J., Gumulya Y., Harris K.L., Janosik T., Jurva U., Sandinge A.S., Saskya E. Carrera-Pacheco, Syed P., Thomson R.E.S.

Fuentes:

scopus