Mostrando 3 resultados de: 3
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Article(3)
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Archives of Biochemistry and Biophysics(1)
Biochemistry(1)
Journal of Steroid Biochemistry and Molecular Biology(1)
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Bioquímica(3)
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scopus(3)
Catalytic modulation of human cytochromes P450 17A1 and P450 11B2 by phospholipid
ArticleAbstract: Unlike most of the drug-metabolizing cytochrome P450s, microsomal P450 17A1 and mitochondrial P450 1Palabras claves:P450 11B2, P450 17A1, phospholipidAutores:Barlow C., Peng H.M., Richard J. AuchusFuentes:scopusMinor activities and transition state properties of the human steroid hydroxylases cytochromes P450c17 and P450c21, from reactions observed with deuterium-labeled substrates
ArticleAbstract: The steroid hydroxylases CYP17A1 (P450c17, 17-hydroxylase/17,20-lyase) and CYP21A2 (P450c21, 21-hydrPalabras claves:Autores:Matthew S., Peng H.M., Richard J. Auchus, Sharma K.K., Stidd D., Yoshimoto F.K., Yoshimoto J.A., Zhou Y.Fuentes:scopusTwo surfaces of cytochrome b<inf>5</inf> with major and minor contributions to CYP3A4-catalyzed steroid and nifedipine oxygenation chemistries
ArticleAbstract: Conserved human cytochrome b5 (b5) residues D58 and D65 are critical for interactions with CYP2E1 anPalabras claves:Allostery, CYP3A4, Cytochrome b 5, Cytochrome p450, Drug oxidation, TestosteroneAutores:Peng H.M., Richard J. AuchusFuentes:scopus