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Neuronal cell cycle re-entry markers are altered in the senescence accelerated mouse P8 (SAMP8)
ArticleAbstract: Senescence-accelerated mice 8 (SAMP8), a model of aging, display many established pathological featuPalabras claves:aging, Alzheimer's disease, CDK5, cell cycle, GSK3β, TauAutores:Antoni Camins, Casadesús G., Gutiérrez-Cuesta J., Jiménez A., Lee H.g., Ortuo-Sahagún D., Pallás M., Smith M.A., Tajes M.Fuentes:scopusNeuroprotective effects of the amylin analog, pramlintide, on Alzheimer's disease are associated with oxidative stress regulation mechanisms
ArticleAbstract: Administration of the recombinant analog of the pancreatic amyloid amylin, Pramlintide, has shown thPalabras claves:Alzheimer's disease, amylin, metabolism, neuroprotection, Oxidative Stress, pramlintideAutores:Antoni Camins, Blair J., Casadesús G., Corrigan R., Grizzanti J., Lee H.g., Mey M., Pallás M., Patrick S.Fuentes:scopusUnveiling "the switch" from aging to Alzheimer's disease with the senescence-accelerated mouse model (SAMP8)
ReviewAbstract: Current mouse models of Alzheimer's disease (AD) are restricted to the expression of AD-related pathPalabras claves:aging, Alzheimer's disease, Amyloid-β, Animal models, COGNITION, Gliosis, Neurodegeneration, Oxidative Stress, SAMP8, Tau phosphorylationAutores:Antoni Camins, Casadesús G., Chang J., Kim H.J., Lee H.g., Pallás M., Perry G., Smith M.A., Zhu X.Fuentes:scopusThe effect of mGluR2 activation on signal transduction pathways and neuronal cell survival
ArticleAbstract: In earlier studies, we found profound alterations in specific signal transduction pathways such as mPalabras claves:ERK, mGluR2, neuroprotectionAutores:Antoni Camins, Casadesús G., Lee H.g., Nakanishi S., O'Neill M.J., Pallás M., Perry G., Smith M.A., Zhu X.Fuentes:scopusThe sirtuin pathway in ageing and Alzheimer disease: Mechanistic and therapeutic considerations
OtherAbstract: Background: Advances in gerontology have yielded crucial insights into the molecular and biochemicalPalabras claves:Autores:Antoni Camins, Bonda D.J., Casadesús G., Lee H.g., Pallás M., Smith M.A., Zhu X.Fuentes:scopusThe therapeutic potential of metabolic hormones in the treatment of age-related cognitive decline and Alzheimer's disease
ReviewAbstract: Aging leads to a number of physiological alterations, specifically changes in circulating hormone lePalabras claves:Alzheimer disease, amylin, DIABÉTES, Insulin, leptin, obesityAutores:Antoni Camins, Casadesús G., Grizzanti J., Lee H.g., Pallás M.Fuentes:scopus