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Chronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype, and TP53 disruption
ArticleAbstract: The presence of expanded proliferation centers (PCs) in lymph nodes involved by chronic lymphocyticPalabras claves:Bone marrow, Chronic lymphocytic leukemia/small lymphocytic lymphoma, Complex karyotype, Proliferation centers, TP53Autores:Bueso-Ramos C., Hu S., Kanagal-Shamanna R., Khoury J.D., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Salem A., Schlette E., Sofía A. Garcés, Tang G., Wang S.A.Fuentes:scopusConcurrent Mutations in SF3B1 and PHF6 in Myeloid Neoplasms
ArticleAbstract: It has been reported that gene mutations in SF3B1 and PHF6 are mutually exclusive. However, this obsPalabras claves:myeloid neoplasms, PHF6, SF3B1Autores:Chien K.S., Garcia-Manero G., Jelloul F.Z., Kanagal-Shamanna R., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Sofía A. Garcés, Yin C.C., Zuo Z.Fuentes:scopusAcquired WT1 mutations contribute to relapse of NPM1-mutated acute myeloid leukemia following allogeneic hematopoietic stem cell transplant
ArticleAbstract: The role of WT1 protein in hematopoiesis and leukemogenesisis incompletely elucidated. WT1 overexprePalabras claves:Autores:DiNardo C.D., El Hussein S., Fang H., Furudate K., Kanagal-Shamanna R., Khoury J.D., Loghavi S., Lyapichev K.A., Medeiros L.J., Ok C.Y., Patel K.P., Ravandi F., Routbort M.J., Sofía A. Garcés, Takahashi K., Wang S.A.Fuentes:scopusNon-coding NOTCH1 mutations in chronic lymphocytic leukemia negatively impact prognosis
OtherAbstract:Palabras claves:Autores:Bassett R.L., Floyd K., Jain N., Jelloul F.Z., Kanagal-Shamanna R., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Sofía A. Garcés, Thompson P.A., Wang P., Wierda W.G., Yang R.K., Yin C.C., Zuo Z.Fuentes:scopusLandscape of NOTCH1 mutations and co-occurring biomarker alterations in chronic lymphocytic leukemia
ArticleAbstract: NOTCH1 is one of the most frequently mutated genes in chronic lymphocytic leukemia and has emerged aPalabras claves:Chronic lymphocytic leukemia, Coding, Non-coding, NOTCH1 mutationsAutores:Bassett R.L., Floyd K., Jain N., Jelloul F.Z., Kanagal-Shamanna R., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Sofía A. Garcés, Thompson P.A., Wierda W.G., Yang R.K., Yin C.C., Zuo Z.Fuentes:scopusHematogones with light chain restriction: A potential diagnostic pitfall when using flow cytometry analysis to assess bone marrow specimens
ArticleAbstract: Light-chain restricted hematogones (LCR HGs) detected by flow cytometry analysis can mimic bone marrPalabras claves:Daratumumab, Flow cytometry analysis, Hematogones, Light chain restricted hematogones, Lymphoma, MyelomaAutores:Challagundla P., El Hussein S., Fang H., Jorgensen J.L., Loghavi S., Lyapichev K.A., Medeiros L.J., Qiu L., Sofía A. Garcés, Tashakori M., Wang S.A., Wang W., Wang X.Fuentes:scopus