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Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses
ArticleAbstract: COVID-19 is associated with neurological complications including stroke, delirium and encephalitis.Palabras claves:Autoantibodies, Brain injury, covid-19, neuroinflammationAutores:Allinson K., Allison J., Alvio G., Ansaripour A., Anwar F., Ashton N.J., Baker S., Barcenas-Morales G., Bergamaschi L., Bermperi A., Betancourt A., Bhatti J., Biggs H., Bong S.H., Bower G., Bradley J.R., Breen G., Brookes K., Bucke A., Bullman B., Bullmore E.T., Bunclark K., Burnstein R.M., Butcher H., Caddy S., Calder J., Caller L., Canna L., Caputo D., Cavanagh J., Chandler M., Chatfield D.A., Chaudhry Y., Chinnery P.F., Christmas D., Clapham-Riley D., Coles A.J., Coles J.P., Cooper D., Correia M., Cossetti C., Crucusio C., Das T., Digby R.J., Doffinger R., Dunai C., Dunning J., Ebrahimi S., Edé A., Elmer A., Emma Jones, Fletcher P.C., Fonseca C., Gisslé M., Griffiths M.J., Irani S.R., Jubb A.W., Kingston N., Leibowitz M.M., Lupson V.C., Lyons P.A., Manktelow A.E., Marklund E., Menon D.K., Michael B.D., Michell A., Needham E.J., Newcombe V.F.J., Norton E.J., Openshaw P.J.M., Outtrim J.G., Pointon L., Ren A.L., Rodgers C.T., Rowe J.B., Rua C., Samanta R.J., Sithole N., Smith K.G.C., Spindler L.R.B., Stamatakis E.A., Summers C., Taams L.S., Taussig M.J., Taylor J., Valerio F., Widmer B., Williams G.B., Zetterberg H.Fuentes:scopusAge-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2
ArticleAbstract: Although two-dose mRNA vaccination provides excellent protection against SARS-CoV-2, there is littlePalabras claves:Autores:Abdullahi A., Baker S., Bergamaschi L., Betancourt A., Bower G., Bucke A., Bullman B., Bunclark K., Calder J., Canna L., Collier D.A., Cossetti C., Datir R.P., de Sa A., Domingo J., Dougan G., Dunmore B.J., Eckart E.M., Elmer A., Emma Jones, Epping M., Fawke S., Ferreira I.A.T.M., Fuller S., Gleadall N., Graf S., Grenfell R., Harris J., Hess C., Hewitt S., Hinch A., Hodgson J., Huang C., Huhn O., Hunter K., Jackson S., Jarvis I., Jose S., Josipovic M., Kennet J., Kingston N., Kotagiri P., Kourampa J., Krishna B., Legchenko E., Lehner P.J., Lewis D., Lim E.Y., Lyons P.A., Mackay M., Marsden J., Martin J., Matara C., Matheson N.J., Maxwell P., Meadows A., Meng B., Mescia F., Michael A., Nice F., Okecha G., Omarjee O., Owehand W.H., O’Brien C., O’Donnell C., Perera M., Pointon L., Pond N., Potts M., Price J., Publico C., Rastall R., Ribeiro C., Richoz N., Romashova V., Rossi S., Rowlands J., Ruffolo V., Saunders C., Sharma R., Shaw A., Shih J., Stefanucci L., Stephens J., Strezlecki M., Summers C., Sutcliffe R., Thaventhiran J.E.D., Tilly T., Tong Z., Tordesillas H., Toshner M., Touizer E., Treacy C., Turner L., Weekes M.P., Wood J., Wylot M., Yarkoni N.S.Fuentes:scopusLongitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease
ArticleAbstract: The kinetics of the immune changes in COVID-19 across severity groups have not been rigorously assesPalabras claves:bystander CD8+ T cell, complement, covid-19, immune pathology, INTERFERÓN, recovery, SARS-COV-2, Systemic inflammation, TNF-αAutores:Allison J., Ansaripour A., Baker S., Bergamaschi L., Betancourt A., Bong S.H., Bower G., Bradley J.R., Bucke A., Bullman B., Bunclark K., Butcher H., Calder J., Calero-Nieto F.J., Canna L., Caputo D., Clapham-Riley D., Cossetti C., Coudert J.D., de Bie E.M.D.D., de Sa A., Dewhurst E., di Stefano G., Doffinger R., Domingo J., Dougan G., Dunmore B.J., Elmer A., Emma Jones, Epping M., Fahey C., Fawke S., Fuller S., Furlong A., Gerber P.P., Gleadall N., Goodfellow I.G., Göttgens B., Graf S., Graves B., Gray J., Grenfell R., Gupta R.K., Hanson A.L., Harris J., Hess C., Hewitt S., Hinch A., Hodgson J., Holmes E., Hosmillo M., Huang C., Huhn O., Hunter K., Ivers T., Jackson S., Jarvis I., Jose S., Josipovic M., Kasanicki M., Kennet J., Kingston N., Kotagiri P., Kourampa J., Laurenti E., Le Gresley E., Legchenko E., Lehner P.J., Lewis D., Linger R., Lyons P.A., Mackay M., Marioni J.C., Marsden J., Martin J., Matara C., Matheson N.J., Meadows A., Meloy S., Mende N., Mescia F., Michael A., Michel R., Morgan M.D., Muldoon F., Mwaura L., Nice F., Nicholson J.K., Petrunkina A.M., Richardson S., Ruffieux H., Saunders C., Smith K.G.C., Thaventhiran J.E.D., Toonen E.J.M., Toshner M., Turner L., Weekes M.P., Wills M.R.Fuentes:scopusSensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies
ArticleAbstract: Transmission of SARS-CoV-2 is uncontrolled in many parts of the world; control is compounded in somePalabras claves:Autores:Baker S., Bassi J., Bergamaschi L., Bernardo M. Gutierrez, Betancourt A., Bianchi S., Bowen J., Bower G., Bucke A., Bullman B., Calder J., Cameroni E., Canna L., Collier D.A., Cossetti C., Culap K., Datir R.P., De Marco A., de Sa A., Domingo J., Dougan G., Dunmore B.J., Elmer A., Emma Jones, Epping M., Fawke S., Ferreira I.A.T.M., Fuller S., Garzoni C., Graf S., Grenfell R., Harris J., Hess C., Hewitt S., Hinch A., Hodgson J., Huang C., Huhn O., Hunter K., Jackson S., Jaconi S., Jarvis I., Jose S., Kemp S.A., Kennet J., Kingston N., Kourampa J., Legchenko E., Lehner P.J., Lewis D., Lyons P.A., Marsden J., Martin J., Matara C., Matheson N.J., Meadows A., Meng B., Mescia F., Nice F., Okecha G., Omarjee O., Owehand W.H., O’Brien C., O’Donnell C., Pellanda A.F., Perera M., Pinto D., Pizzuto M.S., Pointon L., Pond N., Price J., Publico C., Rastall R., Ribeiro C., Richoz N., Riva A., Romashova V., Rowlands J., Ruffolo V., Saunders C., Sharma R., Shih J., Silacci-Fregni C., Snell G., Stefanucci L., Stephens J., Strezlecki M., Summers C., Sutcliffe R., Thaventhiran J.E.D., Tilly T., Tong Z., Tordesillas H., Tortorici M.A., Toshner M., Treacy C., Walls A.C., Weekes M.P., Wood J., Wylot M., Yarkoni N.S.Fuentes:scopusSingle-cell multi-omics analysis of the immune response in COVID-19
ArticleAbstract: Analysis of human blood immune cells provides insights into the coordinated response to viral infectPalabras claves:Autores:Bacardit J., Bach K., Baker K.F., Baker S., Barnes J.L., Barr A.S., Bergamaschi L., Botting R.A., Bradley J.R., Bucke A., Bullman B., Calder J., Calero-Nieto F.J., Canna L., Coupland P., Coxhead J.M., Dann E., de Wilton A., Domingo J., Dougan G., Dunmore B.J., Elmer A., Emma Jones, Engelbert J., Fawke S., Fuller S., Gardner L.C.S., Goh I., Goodfellow I.G., Gopee N., Gothe F., Graf S., Gupta R.K., Hanrath A.T., Harris J., Hess C., Hewitt S., Hodgson J., Horsfall D., Huang C., Huang N., Hunter K., Janes S.M., Jardine L., Jose S., Kania K., Kennet J., Kilich E., King H.W., Kingston N., Kiselev V.Y., Kourampa J., Kumasaka N., Legchenko E., Lehner P.J., Lindeboom R.G.H., Matara C., Mather M.W., Matheson N.J., McGrath J., Meadows A., Mende N., Mescia F., Morgan M.D., Olabi B., Owehand W.H., O’Brien C., Payne R.P., Polanski K., Price J., Prigmore E., Publico C., Rastall R., Reynolds G., Ribeiro C., Rowlands J., Ruffolo V., Saigal A., Saleh A., Sanchez-Gonzalez A., Saunders C., Schim van der Loeff I.C.D., Scott J., Smith C.M., Smith K.G.C., Spegarova J.S., Stephenson E., Summers C., Sungnak W., Thaventhiran J.E.D., Tordesillas H., Toshner M., Tuong Z.K., van Dongen S., Webb S., Weekes M.P., Wilson C., Wilson N.K., Worlock K.B., Yoshida M.Fuentes:scopus