Mostrando 3 resultados de: 3
Cytotoxic and apoptosis-inducing effect of ent-15-oxo-kaur-16-en-19-oic acid, a derivative of grandiflorolic acid from Espeletia schultzii
ArticleAbstract: ent-Kaurenic acid and many natural derivatives of this diterpene are known to have interesting bioloPalabras claves:apoptosis, ent-5-Oxo-kaur-16-en-19-oic acid, ent-Kaurenoids, Espeletia schultzii, Espeletiinae, Frailejón, PC-3 cell lineAutores:Arvelo F.A., Galindo-Castro I., Monsalve M., Nardy Diez, Rodrigues J.R., Ruiz Y., Usubillaga A.Fuentes:googlescopusCytotoxic and proapoptotic activity of ent-16β-17α- dihydroxykaurane on human mammary carcinoma cell line MCF-7
ArticleAbstract: Here we describe the cytotoxic and proapoptotic effect of an ent-kaurane (ent-16β-17α-dihydroxykauraPalabras claves:Anticancer agents, apoptosis, BCL2, Cytotoxic activity, Ent-kaurane, Telomerase activityAutores:Alírica Isabel Suárez, Arvelo F.A., Compagnone R.S., Galindo-Castro I., Luis Ramírez J., Mendoza R., Morales A., Pérez P.Fuentes:scopusThe marine sponge toxin agelasine B increases the intracellular Ca <sup>2+</sup> concentration and induces apoptosis in human breast cancer cells (MCF-7)
ArticleAbstract: Purpose: In search for new drugs derived from natural products for the possible treatment of cancer,Palabras claves:Agelasine B, calcium, Natural products, SERCA, ThapsigarginAutores:Alírica Isabel Suárez, Arvelo F.A., Benaím G., Chirino P., Colman L., Compagnone R.S., de Sanctis J.B., Dipolo R., Felibertt P., Galindo-Castro I., Mayora A., Pimentel A.A., Rojas H., Silva M.L., Sojo F.J.Fuentes:scopus