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Characterization of Spatiooral Cardiac Action Potential Variability at Baseline and under β-Adrenergic Stimulation by Combined Unscented Kalman Filter and Double Greedy Dimension Reduction
ArticleAbstract: Objective: Elevated spatiooral variability of human ventricular repolarization has been related to iPalabras claves:Cardiac electrophysiological models, double greedy dimension reduction, joint estimation, Parameter estimation, spatiooral variability, Unscented kalman filterAutores:Esther Pueyo, Fernandez-Bes J., Lombardi D., Pablo Laguna, Raphel F., Sampedro-Puente D.A.Fuentes:scopusComplex Interaction Between Low-Frequency APD Oscillations and Beat-to-Beat APD Variability in Humans Is Governed by the Sympathetic Nervous System
ArticleAbstract: Background: Recent clinical, experimental and modeling studies link oscillations of ventricular repoPalabras claves:Action potential duration, Beat-to-beat variability, beta-adrenergic blockade, Human heart, oscillations, SympatheticAutores:Bishop M.J., Duijvenboden S.V., Esther Pueyo, Fernandez-Bes J., Gill J.S., Gould J., Hanson B., Lambiase P.D., Orini M., Porter B., Razavi R., Rinaldi C.A., Sampedro-Puente D.A., Sidhu B., Taggart P.Fuentes:scopusData-Driven Identification of Stochastic Model Parameters and State Variables: Application to the Study of Cardiac Beat-to-Beat Variability
ArticleAbstract: Enhanced spatiotemporal ventricular repolarization variability has been associated with ventricularPalabras claves:Beat-to-beat variability, Cardiac electrophysiological models, joint estimation, Parameter estimation, Unscented kalman filterAutores:Esther Pueyo, Fernandez-Bes J., Sampedro-Puente D.A., Varro A., Virag L.Fuentes:scopusEmerging evidence for a mechanistic link between low-frequency oscillation of ventricular repolarization measured from the electrocardiogram T-wave vector and arrhythmia
ReviewAbstract: Strong recent clinical evidence links the presence of prominent oscillations of ventricular repolariPalabras claves:Action potential duration, arrhythmia, Beta-Adrenergic stimulation, electrophysiology, low-frequency oscillations, Mechano-electric feedback, Repolarization, T waveAutores:Bishop M.J., Duijvenboden S.V., Esther Pueyo, Gill J.S., Hanson B., Lambiase P.D., Orini M., Porter B., Rinaldi C.A., Sampedro-Puente D.A., Taggart P.Fuentes:scopusDifferential responses to beta-adrenergic stimulation in the long-qt syndrome type 1: Characterization and mechanisms
Conference ObjectAbstract: Long QT syndrome type 1 (LQT1) is caused by mutations that impair the function of the slow delayed rPalabras claves:Autores:Esther Pueyo, Fernandez-Bes J., Sampedro-Puente D.A.Fuentes:scopusIn Silico Characterization of Repolarization Duration and Variability in the Long QT1 Syndrome under ß-Adrenergic Stimulation
Conference ObjectAbstract: Enhanced temporal repolarization variability facilitates ventricular arrhythmias in the long QT 1 (LPalabras claves:Autores:Esther Pueyo, Fernandez-Bes J., Lombardi D., Pablo Laguna, Raphel F., Sampedro-Puente D.A.Fuentes:scopusMechanisms underlying interactions between low-frequency oscillations and beat-to-beat variability of celullar ventricular repolarization in response to sympathetic stimulation: Implications for arrhythmogenesis
ArticleAbstract: Background and Objectives: Enhanced beat-to-beat variability of ventricular repolarization (BVR) hasPalabras claves:arrhythmogenesis, Beat-to-beat variability, Beta-Adrenergic stimulation, cardiac cell models, low-frequency oscillations, Stochasticity, Sympathetic provocationAutores:Esther Pueyo, Fernandez-Bes J., Porter B., Sampedro-Puente D.A., Taggart P., Van Duijvenboden S.Fuentes:scopusIdentification of parameters describing phenomenological cardiac action potential models using sigma-point methods
Conference ObjectAbstract: Phenomenological action potential (AP) models allow reproducing characteristic features of cardiomyoPalabras claves:Autores:Esther Pueyo, Fernandez-Bes J., Sampedro-Puente D.A.Fuentes:scopusTime Course of Low-Frequency Oscillatory Behavior in Human Ventricular Repolarization Following Enhanced Sympathetic Activity and Relation to Arrhythmogenesis
ArticleAbstract: Background and Objectives: Recent studies in humans and dogs have shown that ventricular repolarizatPalabras claves:arrhythmogenesis, Beta-Adrenergic stimulation, cardiac cell models, low-frequency oscillations, sympathetic activity, Ventricular repolarizationAutores:Esther Pueyo, Fernandez-Bes J., Nánási P.P., Sampedro-Puente D.A., Szentandrássy N., Taggart P.Fuentes:scopus