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From Ugi Multicomponent Reaction to Linkers for Bioconjugation
ArticleAbstract: Bioconjugation is a key approach for the development of novel molecular entities with clinical appliPalabras claves:Autores:Alberício F., Cuevas C., Domínguez J.M., Hortensia Rodriguez Cabrera, Pérez-Chacon G., Ramos-Tomillero I., Sánchez‐Madrid F., Somovilla-Crespo B., Zapata J.M.Fuentes:googlescopusStructure-Acid Lability Relationship of N-alkylated α,α-dialkylglycine Obtained via a Ugi Multicomponent Reaction
ArticleAbstract: Using the classical Ugi four-component reaction to fuse an amine, ketone, carboxylic acid, and isocyPalabras claves:acidolysis study, N-alkylated α,α-dialkylglycine, structure-acid lability, Ugi multicomponent reactionAutores:Alberício F., Hortensia Rodriguez Cabrera, Marisa K. Sánchez, Ramos-Tomillero I.Fuentes:scopusTetrahydropyranyl, a nonaromatic acid-labile cys protecting group for fmoc peptide chemistry
ArticleAbstract: Tetrahydropyranyl (Thp), which exploits the concept of being an S,O-acetal nonaromatic protecting grPalabras claves:Autores:Alberício F., Hortensia Rodriguez Cabrera, Ramos-Tomillero I.Fuentes:googlescopusTetrahydropyranyl: A Non-aromatic, Mild-Acid-Labile Group for Hydroxyl Protection in Solid-Phase Peptide Synthesis
ArticleAbstract: The use of the tetrahydropyranyl (Thp) group for the protection of serine and threonine side-chain hPalabras claves:Protecting groups, serine, Solid-phase peptide synthesis, tetrahydropyranyl group, threonineAutores:Alberício F., B. G. De la Torre, El-Faham A., Hortensia Rodriguez Cabrera, Ramos-Tomillero I., Sharma A.Fuentes:scopus