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International Journal of Molecular Sciences(1)
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Farmacología y terapéutica(5)
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From Genetic Engineering to Preclinical Safety: A Study on Recombinant Human Interferons
ArticleAbstract: There is a critical gap in the preclinical research of recombinant human interferons (rhIFNα-2b andPalabras claves:animal model, Antiproliferative, antiviral, bioactivity, Immunomodulatory, interferon alpha, Interferon gamma, Preclinical, Recombinant, toxicityAutores:Cristy N. Culqui-Tapia, Felipe Sandoval, Ignacio Cabezas, Lamazares E., Mansilla R., María A. Contreras, Parra N.C., Sanchez O., Santiago Nelson Vispo, Sarah Martin-Solano, Sergio Donoso-Erch, Thelvia I. Ramos Gómez, Viana Manrique-Suárez, Villacis-Aguirre C.A.Fuentes:scopusExpression and Characterization of Human Vascular Endothelial Growth Factor Produced in SiHa Cells Transduced with Adenoviral Vector
ArticleAbstract: The vascular endothelial growth factor (VEGF) is an essential factor to pathologic angiogenesis. DisPalabras claves:Adenoviral vector, ECV-304 cells, HUVEC, Vascular permeability, VEGF 121, VEGF121Autores:Aedo G., Camacho F., Castillo C., González-Chavarría I., González-Horta E.E., Mansilla R., Parra N.C., Sanchez O., Santiago Nelson VispoFuentes:scopusPolymeric nanoencapsulation of alpha interferon increases drug bioavailability and induces a sustained antiviral response in vivo
ArticleAbstract: Polymeric nanoparticulate systems allow the encapsulation of bio-active substances, giving them protPalabras claves:Antiviral interferon, drug delivery, Ionotropic gelation, Nanoparticles, Porcine industryAutores:Altamirano C., Fernandez K., Fleitas-Salazar N., Gómez-Gaete C., Lamazares E., Mansilla R., Marlon Alexander Gancino Guevara, Marlon Gancino, Ruiz A., Santana S.P., Toledo J.R.Fuentes:googlescopusDevelopment and characterization of a novel variant of long-acting bovine follicle-stimulating hormone (brscFSH)
ArticleAbstract: Assisted reproduction is a key aspect of modern animal breeding, providing valuable assistance in imPalabras claves:Assisted reproduction, Follicle-stimulating hormone, Recombinant protein, SuperovulationAutores:Acosta J., Eduardo H. Escribano, Florence Hugues, Frank Camacho Casanova, Garcia-Herreros M.G., Gutiérrez-Reinoso M.A., Kaio Tavares, Leonardo Martins, Mansilla R., Montesino R., Moreno E., Oscar Ignacio Cabeza, Parra N.C., Raul Castillo, Rita Cerro, Rodriguez-Alvarez L., Roxana Zuniga Sanchez, Sanchez O., Saul Gaudencio, Toledo J.R.Fuentes:scopusQuadruple therapies are superior to standard triple therapy for Helicobacter pylori first-line eradication in Chile
ArticleAbstract: Introduction: Helicobacter pylori infection affects approximately 70% of the Chilean population. ItPalabras claves:Antibiotic Resistance, Eradication rates, helicobacter pyloriAutores:Alberto Espino, Alex Arenas, Andrea Gallardo, Antonio Rollán, Diego Cordova Reyes, Fuentes-López E., Javier Chahuan, Javier Ortiz, Javiera Godoy, Jose Ignacio Vargas, Mansilla R., Margarita Pizarro, María Francisca Seydewitz, María Paz Rollan, Riquelme-Pérez A., Roberto Candia, Sigall Budnik, Vicente GandaraFuentes:scopus