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Frontiers in Pharmacology(2)
International Journal of Molecular Sciences(1)
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Neurotoxicity Research(1)
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scopus(7)
A2AR transmembrane 2 peptide administration disrupts the A2AR-A2AR homoreceptor but not the A2AR-D2R heteroreceptor complex: Lack of actions on rodent cocaine self-administration
ArticleAbstract: It was previously demonstrated that rat adenosine A2AR transmembrane V peptide administration into tPalabras claves:Adenosine A2A receptor, Allosteric receptor–receptor interactions, cocaine use disorder, dopamine D2 receptor, Heteroreceptor complexes, Homoreceptor complexes, Small interfering peptides: G protein-coupled receptorsAutores:Borroto-Escuela D.O., Filip M., Frankowska M., Fuxe K., W. Romero-Fernandez, Wydra K., Zhou Z.Fuentes:scopusAcute Cocaine Enhances Dopamine D<inf>2</inf>R Recognition and Signaling and Counteracts D<inf>2</inf>R Internalization in Sigma1R-D<inf>2</inf>R Heteroreceptor Complexes
ArticleAbstract: The current study was performed to establish the actions of nanomolar concentrations of cocaine, notPalabras claves:Cocaine, dimerization, dopamine D2 receptor, Heteroreceptor complexes, Oligomerization, Sigma 1 receptor, Substance use disorderAutores:Beggiato S., Borroto-Escuela D.O., Ferraro L., Filip M., Fuxe K., Narváez M., Pinton L., Tanganelli S., W. Romero-Fernandez, Wydra K.Fuentes:scopusAcute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor–receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels
ArticleAbstract: Background: Antagonistic adenosine A2A receptor (A2AR)-dopamine D2 receptor (D2R) receptor–receptorPalabras claves:Adenosine A2A receptor, Cocaine, dopamine D2 receptor, Heteroreceptor complexes, Sigma1 receptorAutores:Beggiato S., Borroto-Escuela D.O., Ferraro L., Filip M., Fuxe K., Tanganelli S., W. Romero-Fernandez, Wydra K., Zhou Z.Fuentes:scopusOSU-6162, a Sigma1R Ligand in Low Doses, Can Further Increase the Effects of Cocaine Self-Administration on Accumbal D2R Heteroreceptor Complexes
ArticleAbstract: Cocaine was previously shown to act at the Sigma1R which is a target for counteracting cocaine actioPalabras claves:A2AR-D2R heteroreceptor complexes, allosteric receptor-receptor interactions, cocaine use disorder, monoamine stabilizerAutores:Borroto-Escuela D.O., Filip M., Fuxe K., Suder A., W. Romero-Fernandez, Wydra K., Zhou Z.Fuentes:scopusMapping the interface of a GPCR Dimer: A structural model of the A<inf>2A</inf> Adenosine and D<inf>2</inf> dopamine receptor heteromer
ArticleAbstract: The A2A adenosine (A2AR) and D2 dopamine (D2R) receptors form oligomers in the cell membrane and allPalabras claves:A adenosine receptor 2A, allosteric modulation, D dopamine receptor 2, Dimer interface, dimerization, G protein-coupled receptor, Heteroreceptor complexAutores:Borroto-Escuela D.O., Carlsson J., Fuxe K., Jaiteh M., Kapla J., Lazarova T., Ranganathan A., Rodriguez D., W. Romero-FernandezFuentes:scopusReceptor–receptor interactions in multiple 5-HT1A heteroreceptor complexes in raphe-hippocampal 5-HT transmission and their relevance for depression and its treatment
ReviewAbstract: Due to the binding to a number of proteins to the receptor protomers in receptor heteromers in the bPalabras claves:Depression, Fibroblast growth factor receptor, G protein-coupled receptors, Galanin, Heteroreceptor complexes, Oligomerization, Receptor tyrosine kinase, Receptor-receptor interactions, Serotonin 5-HT1A receptorAutores:Ambrogini P., Andrade-Talavera Y., Borroto-Escuela D.O., Brito I., Díaz-Cabiale Z., Ferraro L., Flores-Burgess A., Fuxe K., Gago B., Millón C., Narvaez J.A., Narváez M., Odagaki Y., Palkovits M., W. Romero-FernandezFuentes:scopusThe Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders
ArticleAbstract: The widespread distribution of heteroreceptor complexes with allosteric receptor-receptor interactioPalabras claves:Adenosine A2A receptor, cocaine use disorder, dopamine D2 receptor, G protein-coupled receptor, morphine use disorder, mu opioid receptor, oligomerization, morphineAutores:Beggiato S., Borroto-Escuela D.O., Crespo-Ramirez M., Ferraro L., Filip M., Fores-Pons R., Frankowska M., Fuxe K., Perez de la Mora M., Rivera A., Rocha L.L., Stove C., Vasudevan L., W. Romero-Fernandez, Wydra K.Fuentes:scopus