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Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular(2)
Clinical Pharmacology and Therapeutics(2)
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 and CYP2C19 genotypes and dosing of selective serotonin reuptake inhibitors
ArticleAbstract: Selective serotonin reuptake inhibitors (SSRIs) are primary treatment options for major depressive aPalabras claves:Autores:Adrián LLerena, Bishop J.R., Caudle K.E., Chiulli D.L., Gaedigk A., Graham R.L., Hicks J.K., Ji Y., Klein T.E., Leckband S.G., Leeder J.S., Muller D.J., Sangkuhl K., Scott S.A., Skaar T.C., Stingl J.C.Fuentes:scopusA Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy
OtherAbstract:Palabras claves:Autores:Adrián LLerena, Bishop J.R., Bousman C.A., Caudle K.E., Gaedigk A., Gammal R.S., Hicks J.K., Klein T.E., Leeder J.S., Muller D.J., Ramsey L.B., Sangkuhl K., Scott S.A., Skaar T.C.Fuentes:scopusSeparation of electronic and hydrophobic effects for the papain hydrolysis of substituted N-benzoylglycine esters
ArticleAbstract: The role of hydrophobic and electronic effects on the kinetic constants kcat and Km for the papain hPalabras claves:Enzymic hydrolysis, Glycinate ester, N-Benzoylglycine ester, Papain, QSAR, SARAutores:Cesar M. Compadre, Hansch C., Klein T.E., Nelson Smith R., Petridou-Fischer J., Selassie C., Steinmetz W., Yang C., Yang G.Fuentes:scopusThe structure-activity relationship of the papain hydrolysis of N-benzoylglycine esters
ArticleAbstract: The relationship between structure and the Michaelis-Menten constants (Km) for the papain hydrolysisPalabras claves:Hydrolysis, Molecular graphics, N-Benzoylglycine ester, Papain, QSARAutores:Cesar M. Compadre, Hansch C., Klein T.E., Langridge R.Fuentes:scopus