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In vitro neuroprotective and anti-inflammatory activities of natural and semi-synthetic spirosteroid analogues
ArticleAbstract: Two spirosteroid analogues were synthesized and evaluated for their in vitro neuroprotective activitPalabras claves:Excitotoxicity, inflammatory mediators, neuroprotection, SpirosteroidsAutores:Exarchou V., García-Pupo L., Juan Enrique Tacoronte-Morales, Núñez-Figueredo Y., Pieters L., René D.H., Vanden Berghe W., Zaldo-Castro A.Fuentes:scopusMethylated flavonoids as anti-seizure agents: Naringenin 4′,7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models
ArticleAbstract: Epilepsy is a neurological disease that affects more than 70 million people worldwide and is charactPalabras claves:Drug Discovery, Epilepsy, Methylated flavonoids, mouse, Naringenin, zebrafishAutores:Adriana Orellana-Paucar, Copmans D., De Borggraeve W., De Witte P.A.M., Dehaen W., Exarchou V., Foubert K., Kim Y., Ny A., Pieters L., Siekierska A., Steurs G., Zhang Y.Fuentes:googlescopus