Mostrando 5 resultados de: 5
Subtipo de publicación
Article(5)
Publisher
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences(2)
Clinical Chemistry and Laboratory Medicine(1)
European Journal of Drug Metabolism and Pharmacokinetics(1)
Journal of Affective Disorders(1)
Área temáticas
Farmacología y terapéutica(4)
Bioquímica(3)
Enfermedades(2)
Química y ciencias afines(2)
Criminología(1)
Objetivos de Desarrollo Sostenible
ODS 3: Salud y bienestar(5)
ODS 9: Industria, innovación e infraestructura(3)
ODS 10: Reducción de las desigualdades(1)
ODS 17: Alianzas para lograr los objetivos(1)
Origen
scopus(5)
Analysis of diclofenac and its metabolites by high-performance liquid chromatography: Relevance of CYP2C9 genotypes in diclofenac urinary metabolic ratios
ArticleAbstract: In humans, diclofenac is metabolised to 4′-hydroxy (OH), 3′-OH and 5-OH metabolites. The polymorphicPalabras claves:CYP2C9 genotypes, Diclofenac, HydroxydiclofenacAutores:Adrián LLerena, Berecz R., Cáceres M.C., Dorado P.Fuentes:scopusDetermination of debrisoquine and 4-hydroxydebrisoquine by high-performance liquid chromatography: Application to the evaluation of CYP2D6 genotype and debrisoquine metabolic ratio relationship
ArticleAbstract: The drug-metabolizing cytochrome P450 (CYP) enzyme CYP2D6 is involved in the metabolism of several cPalabras claves:CYP2D6, debrisoquine, HPLC, Metabolic ratioAutores:Adrián LLerena, Berecz R., Cáceres M.C., Cobaleda J., Dorado P., González I.Fuentes:scopusDetermination of fluoxetine and norfluoxetine in human plasma by high-performance liquid chromatography with ultraviolet detection in psychiatric patients
ArticleAbstract: A rapid high-performance liquid chromatographic method is described for the simultaneous determinatiPalabras claves:Fluoxetine, NorfluoxetineAutores:Adrián LLerena, Berecz R., Cáceres M.C., De la Rubia A., Dorado P., González A.P., Jesus Norberto M.Fuentes:scopusReduced completed suicide rate in Hungary from 1990 to 2001: Relation to suicide methods
ArticleAbstract: Background and method: Changes in the rate of completed suicides and in the suicide methods used inPalabras claves:Completed suicide, Mortality , Poisoning, Toxic substancesAutores:Adrián LLerena, Bartók E., Berecz R., Cáceres M.C., Degrell I., Dorado P., Penãs-Lledó E.M., Szlivka A.Fuentes:scopusReproducibility over time of the urinary diclofenac/4′-OH diclofenac ratio among different CYP2C9 genotypes
ArticleAbstract: Diclofenac has been used for the evaluation of CYP2C9 activity in vitro as well as in vivo with varyPalabras claves:CYP2C9, Cytochrome p450, Diclofenac, LOSARTÁNAutores:Adrián LLerena, Berecz R., Cáceres M.C., Conzález I., Dorado P.Fuentes:scopus