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A novel and basic mechanism of immunosuppression in Chagas' disease: Trypanosoma cruzi releases in vitro and in vivo a protein which induces T cell unresponsiveness through specific interaction with cysteine and glutathione
ArticleAbstract:Palabras claves:Cysteine, Glutathione, Immunosuppression, Tc52 protein, TRYPANOSOMA CRUZIAutores:Angel Guevara-Espinoza, Chabé F., Gomez-Corvera R., Ouaissi A., Taibi A.Fuentes:googlescopusErratum: Improved specificity of Trypanosoma cruzi identification by polymerase chain reaction using an oligonucleotide derived from the amino-terminal sequence of a Tc24 protein (Parasitology (1995) 11, (581-590))
OtherAbstract:Palabras claves:Autores:Angel Guevara-Espinoza, Ouaissi A., Schoneck R., Taibi A., Yahiaoui B.Fuentes:googlescopusN-Acetylcysteine and glutathione modulate the behaviour of Trypanosoma cruzi experimental infection
ArticleAbstract:Palabras claves:Glutathione monoester, Immunoregulation, N-acetylcysteine, TRYPANOSOMA CRUZIAutores:Ángel Gustavo Guevara, Borges M., Da Silva A., Guilvard E., Ouaissi A.Fuentes:scopusMolecular and immunological characterization of a Trypanosoma cruzi protein homologous to mammalian elongation factor 1 gamma
ArticleAbstract: In previous studies, we reported the characterization of three Trypanosoma cruzi proteins with molecPalabras claves:EF-1γ, elongation factor, Glutathione S-transferase, TRYPANOSOMA CRUZIAutores:Billaut-Mulot O., Capron A., Loyens M., Ouaissi A., Plumas-Marty B., Pommier V., Rodolfo Fernández-Gómez, Schoneck R., Taibi A.Fuentes:scopusPhenotype of recombinant Trypanosoma cruzi which overexpress elongation factor 1-γ: Possible involvement of EF-1γ GST-like domain in the resistance to clomipramine
ArticleAbstract: In previous studies, molecular and immunological approaches have been used to characterize the TrypaPalabras claves:Drug resistance, Elongation factor 1γ, Transfection, TRYPANOSOMA CRUZIAutores:Billaut-Mulot O., Ouaissi A., Rodolfo Fernández-GómezFuentes:scopusTrypanosoma cruzi : A 6 X histidine-fused Tc24 protein useful for the serological diagnosis of Chagas' disease
ArticleAbstract: A Trypanosoma cruzi protein containing six histidine residues at its N-terminal sequence (6 X his-TcPalabras claves:Autores:Ángel Gustavo Guevara, Billaut-Mulot O., Ouaissi A., Taibi A.Fuentes:scopusTrypanosoma cruzi carrying a targeted deletion of a Tc52 protein-encoding allele elicits attenuated Chagas' disease in mice
ArticleAbstract: The intracellular protozoan parasite Trypanosoma cruzi is the etiological agent of Chagas' disease.Palabras claves:IFN-γ, IL-2, pathology, Tc52 mutant +/-, TRYPANOSOMA CRUZIAutores:Ángel Gustavo Guevara, Borges M., Bosseno M.F., Breniere S.F., Da Silva A., Garzón E., Guilvard E., Meirelles M., Nacife V., Ouaissi A.Fuentes:scopusTrypanosoma cruzi elongation factor 1-α: Nuclear localization in parasites undergoing apoptosis
ArticleAbstract: The cloning and sequencing of the gene coding for Trypanosoma cruzi elongation factor 1α (TcEF-1α) wPalabras claves:Antibodies to Artemia salina EF-1α, Fusion protein, Genomic library, Immunodetection, Programmed cell deathAutores:Billaut-Mulot O., Loyens M., Ouaissi A., Rodolfo Fernández-GómezFuentes:scopusTrypanosoma cruzi isoenzyme variability in Ecuador: First observation of zymodeme III genotypes in chronic chagasic patients
ArticleAbstract: We have analysed by multilocus enzyme electrophoresis (MLEE) at 21 genetic loci 10 Trypanosoma cruziPalabras claves:Chagas disease, ECUADOR, Isoenzyme profiles, Triatoma dimidiata, TRYPANOSOMA CRUZI, ZymodemesAutores:Ángel Gustavo Guevara, Barnabe C., Bowen C., Córdova X., Eduardo A. Gomez-Landires, Garzón E., Ouaissi A., Paredes W., Tibayrenc M.Fuentes:scopusTrypanosoma cruzi-induced host immune system dysfunction: A rationale for parasite immunosuppressive factor(s) encoding gene targeting
ReviewAbstract: An intense suppression of T cell proliferation to mitogens and toantigens is observed in a large numPalabras claves:Autores:Ángel Gustavo Guevara, Borges M., Da Silva A., Guilvard E., Ouaissi A.Fuentes:scopus