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A novel and basic mechanism of immunosuppression in Chagas' disease: Trypanosoma cruzi releases in vitro and in vivo a protein which induces T cell unresponsiveness through specific interaction with cysteine and glutathione
ArticleAbstract:Palabras claves:Cysteine, Glutathione, Immunosuppression, Tc52 protein, TRYPANOSOMA CRUZIAutores:Angel Guevara-Espinoza, Chabé F., Gomez-Corvera R., Ouaissi A., Taibi A.Fuentes:googlescopusN-Acetylcysteine and glutathione modulate the behaviour of Trypanosoma cruzi experimental infection
ArticleAbstract:Palabras claves:Glutathione monoester, Immunoregulation, N-acetylcysteine, TRYPANOSOMA CRUZIAutores:Ángel Gustavo Guevara, Borges M., Da Silva A., Guilvard E., Ouaissi A.Fuentes:scopusTrypanosoma cruzi carrying a targeted deletion of a Tc52 protein-encoding allele elicits attenuated Chagas' disease in mice
ArticleAbstract: The intracellular protozoan parasite Trypanosoma cruzi is the etiological agent of Chagas' disease.Palabras claves:IFN-γ, IL-2, pathology, Tc52 mutant +/-, TRYPANOSOMA CRUZIAutores:Ángel Gustavo Guevara, Borges M., Bosseno M.F., Breniere S.F., Da Silva A., Garzón E., Guilvard E., Meirelles M., Nacife V., Ouaissi A.Fuentes:scopusTrypanosoma cruzi: Analysis of cellular and humoral response against a protective recombinant antigen during experimental Chagas' disease
ArticleAbstract: In previous studies we have shown the protective value of T. cruzi excretory/secretory antigens (ESAPalabras claves:Cellular immunity, Chagas' disesae, Humoral immunity, T cruzi, Tc24Autores:Angel Guevara-Espinoza, Ouaissi A., Taibi A.Fuentes:scopus