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Antihypertensives and Statin Therapy for Primary Stroke Prevention: A Secondary Analysis of the HOPE-3 Tria
ArticleAbstract: Background and Purpose: The HOPE-3 trial (Heart Outcomes Prevention Evaluation-3) found that antihypPalabras claves:Blood pressure, candesartan, Cardiovascular disease, Lipoprotein, Primary Prevention, statinAutores:Avezum A.J., Bosch J.J., Chazova I.E., Dagenais G.R., Gao P., Hart R.G., Held C., Khunti K., Leiter L.A., Lewis B.S., Lonn E.M., Pais P., PATRICIO LOPEZ -JARAMILLO, Peters R.J.G., Reid C.M., Sliwa K., Toff W.D., Yusoff K., Yusuf S., Zhu J.Fuentes:googlescopusDesign and baseline characteristics of participants in the Researching cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) trial on the cardiovascular effects of dulaglutide
ArticleAbstract: The aim was to determine the effects of dulaglutide, a synthetic once-weekly, injectable human glucaPalabras claves:antidiabetic drug, Cardiovascular disease, Clinical trial, diabetes complications, GLP-1 receptor agonistAutores:Atisso C.M., Avezum A.J., Basile J.N., Cardona-Munoz E.G., Chung N., Colhoun H.M., Conget I., Cushman W.C., Dagenais G.R., DIaz R., Franek E., Gerstein H.C., Hâncu N., Hanefeld M., Holt S., Jansky P., Keltai M., Lakshmanan M., Lanas F., Leiter L.A., Pais P., PATRICIO LOPEZ -JARAMILLO, Pirags V., Pogosova N., Probstfield J.L., Raubenheimer P.J., Riddle M.C., Rydén L.E., Shaw J.E., Sheu W.H.H., Temelkova-Kurktschiev T., Xavier D.Fuentes:scopusFixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis
ArticleAbstract: Background: In randomised controlled trials, fixed-dose combination treatments (or polypills) have bPalabras claves:Autores:Avezum A.J., Bangdiwala S.I., Bosch J.J., Castellano J.M., Dagenais G.R., Dans A.M., DIaz R., Fuster V., Gamra H., Gao P., Huffman M.D., Joseph P.G., Liu L., Lonn E.M., Malekzadeh R., Pais P., PATRICIO LOPEZ -JARAMILLO, Prabhakaran D., Rodgers A., Roshandel G., Sliwa K., Teo K.K., Xavier D., Yusuf S., Zhu J.Fuentes:googlescopusDulaglutide and renal outcomes in type 2 diabetes: an exploratory analysis of the REWIND randomised, placebo-controlled trial
ArticleAbstract: Background: Two glucagon-like peptide-1 (GLP-1) receptor agonists reduced renal outcomes in people wPalabras claves:Autores:Abella M., Alebuena A., Almagro S., Amoroso E., Anadon P., Andreu E., Aristimuño G., Arzadun M., Atisso C.M., Avezum A.J., Barbieri M., Barcudi R., BARTOLACCI I.P., Basile J.N., Bolobanich G., BORDONAVA A.P., Botros F.T., Bustamante Labarta M., Bustos B., CACCAVO A., Camino A., Cantero M., Cardona-Munoz E.G., Carignano M., CARTASEGNA L.U.I.S., Chung N., Cipullo M., Colhoun H.M., Commendatore V., Conget I., Conosciuto V., Costamagna O., Crespo C., Cuello J.L., Cuneo C.A., Cushman W.C., Cusimano S., Dagenais G.R., Dean S., DIaz R., Dituro C., Dominguez A., Dyal L., Farah M., Fernandez A., Fernandez F., Ferrari A., Flammia P., Franek E., Fuentealba J., Gallardo K.B., Garcia C., GARCIA DURAN R.O., GARRIDO M., Gavicola R., Gerbaudo C., Gerstein H.C., Gilli G., Giotto A.P., Godoy Bolzán P., Gomez Vilamajo O., Guerlloy F., Guridi C., Gutierrez Garrido N., Hall S., Hâncu N., Hanefeld M., HASBANI E., Hermida S., Holt S., HOMINAL M.A., HRABAR A., Ingaramo A., Izzicupo A., Jansky P., Keltai M., Krynski M., Lagrutta M., Lakshmanan M., Lanas F.T., Lanchiotti P., Langhe M., Leiter L.A., Leonard V., Llanos J., López-Santi R., Pais P., PATRICIO LOPEZ -JARAMILLO, Pirags V., Pogosova N., Probstfield J.L., Rao-Melacini P., Raubenheimer P.J., Riddle M.C., Rydén L.E., Shaw J.E., Sheu W.H.H., Temelkova-Kurktschiev T., Washington Stalin García Cuenta, Wong G., Xavier D.Fuentes:googlescopusEffects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): A randomised controlled trial
ArticleAbstract: Background: Trials of β blockers in patients undergoing non-cardiac surgery have reported conflictinPalabras claves:Autores:Aggarwala R., Alonso-Coello P., Argibay-Poliquin E., Avezum A.J., Badner N., Baer C., Baidel Y., Baptista M., Barratt S., Beattie W.S., Bednarowski M., Beilby D., Bertozzi H.A., Berwanger O., Blacher C., Bodanese L.C., Boisvenu G., Bolsin S., Boulton A., Boyd D., Brunet D., Bryson G.L., Bugler S., Burlingham J., Caccavo R.A., Campeau J., Campos De Albuquerque D., Carlos Zevallos J., Chan M.T.V., Choi P., Chrolavicius S., Ciapponi A., Cope L., Devereaux P.J., Do Amara Baruzzi A.C., Douglas J., Esteves J.P., Faller J., Fatovich S., Ferrari A., Foëx P., França Neto O.R., Gannedahl P., Garcia Dieguez M., Giles J., Goldman L., Grant J., Greenspan L., Guiselli Gallina L.E., Guyatt G.H., Halliwell R., Hudson R.J., Islas Andrade S., Izukawa N.M., Jacka M.J., Kallas F.C., Keltai M., Kerr Saraiva J.F., Kerridge R.K., Leino K., Leslie K., Liu L., Love J., Málaga G., March S., Marin-Neto J.A., Mauricio Espinel, McCulloch T.J., Montori V.M., Myles P.S., Nicolosi L.N., Nigro Maia L., Paech M., Pais P., Penha Rosateli P.H., Peyton P., Phrommintikul A., Pogue J., Poole C., Poustie S., Priestly M., Rabello R., Raeder J., Reeves M., Salazar A., Schammass Ducatti T., Schricker T., Sear J., Sierra F., Tesolin P., Tristan M., Urŕutia G., Wallace S., Warriner B., Weitkamp B., Wolfers D., Xavier D., Xu S., Yang H., Yusuf S.Fuentes:scopusNovel Approaches in Primary Cardiovascular Disease Prevention: The HOPE-3 Trial Rationale, Design, and Participants' Baseline Characteristics
ArticleAbstract: Background: Cholesterol and blood pressure (BP) can be effectively and safely lowered with statin drPalabras claves:Autores:Avezum A.J., Bosch J.J., Chazova I.E., Dagenais G.R., Dans A.M., DIaz R., Fodor G.J., Held C., Jansky P., Keltai K., Keltai M., Kim J.H., Kunti K., Leiter L.A., Lewis B.S., Liu L., Lonn E.M., Pais P., Parkhomenko A.N., PATRICIO LOPEZ -JARAMILLO, Peters R.J.G., Piegas L.S., Pogue J., Reid C.M., Sliwa K., Toff W.D., Varigos J.D., Xavier D., Yusoff K., Yusuf S., Zhu J.Fuentes:googlescopusLowering cholesterol, blood pressure, or both to prevent cardiovascular events: Results of 8.7 years of follow-up of Heart Outcomes Evaluation Prevention (HOPE)-3 study participants
ArticleAbstract: Aims: Rosuvastatin (10 mg per day) compared with placebo reduced major adverse cardiovascular (CV) ePalabras claves:Cardiovascular disease, Primary Prevention, statinsAutores:Avezum A.J., Bosch J.J., Dagenais G.R., Dans A.M., DIaz R., Held C., Jansky P., Joseph P.G., Jung H., Keltai K., Keltai M., Khunti K., Leiter L.A., Lewis B.S., Liu L., Lonn E.M., Pais P., Parkhomenko A.N., PATRICIO LOPEZ -JARAMILLO, Peters R.J.G., Piegas L.S., Reid C.M., Sliwa K., Toff W.D., Varigos J.D., Xavier D., Yusoff K., Yusuf S., Zhu J.Fuentes:googlescopusVariations in knowledge, awareness and treatment of hypertension and stroke risk by country income level
ArticleAbstract: Objective Hypertension is the most important modifiable risk factor for stroke globally. We hypothesPalabras claves:epidemiology, Hypertension, strokeAutores:Alhussain F., Avezum A.J., Chin S.L., Czlonkowska A., Daliwonga M., Damasceno A., Dans A.M., DIaz R., Diener H.C., ElSayed A., Ferguson J., Hankey G.J., Iqbal R., Iversen H.K., Judge C., Lanas F.T., Langhorne P., Lisheng L., Málaga G., Mondo C.K., Nilanont Y., Ogah O.S., Ogunniyi A., Oguz A., Oveisgharan S., O’Donnell M., Pais P., PATRICIO LOPEZ -JARAMILLO, Peñaherrera E., Pogosova N., Rangarajan S., Rao-Melacini P., Rosengren A., Rumboldt Z., Ryglewicz D., Smyth A., Wang X., Weimar C., Xavier D., Yusoff K., Yusuf S., Yusufali A.M., Zhang H.Fuentes:googlescopusRisk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study
ArticleAbstract: Background The contribution of various risk factors to the burden of stroke worldwide is unknown, paPalabras claves:Autores:Chin S.L., Czlonkowska A., Damasceno A., Dans A.M., Denis X., Diener H.C., Hankey G.J., Islam S., Liu L., McQueen M.J., Mondo C.K., O’Donnell M., Pais P., PATRICIO LOPEZ -JARAMILLO, Rangarajan S., Rao-Melacini P., Ryglewicz D., Sacco R.L., Truelsen T., Wang X., Weimar C., Yusoff K., Yusuf S., Zhang H.Fuentes:googlescopusPolypill with or without aspirin in persons without cardiovascular disease
ArticleAbstract: BACKGROUND A polypill comprising statins, multiple blood-pressure-lowering drugs, and aspirin has bePalabras claves:Autores:Bosch J.J., Christou C., Dagenais G.R., Dans A.M., Gamra H., Gao P., Girish P., Joseph P.G., McCready T., Pais P., PATRICIO LOPEZ -JARAMILLO, Rocha C., Santoso A., Talukder S.H., Teo K.K., Tyrwhitt J., Xavier D., Xavier F., Yeates K.E., Yusoff K., Yusuf S.Fuentes:googlescopus