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Chemico-Biological Interactions(1)
Progress in Neuro-Psychopharmacology and Biological Psychiatry(1)
A low-dose combination of ketamine and guanosine counteracts corticosterone-induced depressive-like behavior and hippocampal synaptic impairments via mTORC1 signaling
ArticleAbstract: Ketamine exhibits rapid and sustained antidepressant responses, but its repeated use may cause adverPalabras claves:Augmentation strategy, Corticosterone, Depression, Guanosine, KetamineAutores:Aline Siteneski, Camargo A., Dalmagro A.P., Rodrigues A.L.S., Wolin I.A.V., Zeni A.L.B.Fuentes:googlescopusmTORC1-dependent signaling pathway underlies the rapid effect of creatine and ketamine in the novelty-suppressed feeding test
ArticleAbstract: The development of fast-acting antidepressants is crucial considering that conventional antidepressaPalabras claves:Creatine, Ketamine, mTORC1, Novelty-suppressed feeding testAutores:Aline Siteneski, Camargo A., Fraga D.B., Moretti M., Pazini F.L., Rodrigues A.L.S., Rosa J.M.Fuentes:googlescopus