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Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway
ArticleAbstract: Physical exercise has been shown to exert antidepressant effects, but the mechanisms underlying thisPalabras claves:Antidepressant, FNDC5, Irisin, neurogenesis, physical exerciseAutores:Aline Siteneski, Brocardo P.S., Camargo A., Cunha M.P., Fraga D.B., Gil-Mohapel J., Olescowicz G., Pazini F.L., Rodrigues A.L.S.Fuentes:googlescopusA low-dose combination of ketamine and guanosine counteracts corticosterone-induced depressive-like behavior and hippocampal synaptic impairments via mTORC1 signaling
ArticleAbstract: Ketamine exhibits rapid and sustained antidepressant responses, but its repeated use may cause adverPalabras claves:Augmentation strategy, Corticosterone, Depression, Guanosine, KetamineAutores:Aline Siteneski, Camargo A., Dalmagro A.P., Rodrigues A.L.S., Wolin I.A.V., Zeni A.L.B.Fuentes:googlescopusPhysical exercise stimulates hippocampal mTORC1 and FNDC5/irisin signaling pathway in mice: Possible implication for its antidepressant effect
ArticleAbstract: Several lines of evidence have consistently indicated that physical exercise has antidepressant effePalabras claves:Depression, FNDC5, Irisin, mTORC1, physical exerciseAutores:Aline Siteneski, Brocardo P.S., Camargo A., Freitas A.E., Gruhn K., Olescowicz G., Rodrigues A.L.S.Fuentes:googlescopusPrevalence of major depressive disorder in Portoviejo, Ecuador
ArticleAbstract: Major depressive disorder (MDD) is a debilitating neuropsychiatric disorder that affects more than 3Palabras claves:Depression, ECUADOR, major depressive disorder, Mental Health, PREVALENCEAutores:Aline Siteneski, Camargo A., Diego E. Portalanza, Juan Montalvo-Herdoíza, Mayra PereroFuentes:scopusmTORC1-dependent signaling pathway underlies the rapid effect of creatine and ketamine in the novelty-suppressed feeding test
ArticleAbstract: The development of fast-acting antidepressants is crucial considering that conventional antidepressaPalabras claves:Creatine, Ketamine, mTORC1, Novelty-suppressed feeding testAutores:Aline Siteneski, Camargo A., Fraga D.B., Moretti M., Pazini F.L., Rodrigues A.L.S., Rosa J.M.Fuentes:googlescopus