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Venom diversity in the Neotropical scorpion genus Tityus: Implications for antivenom design emerging from molecular and immunochemical analyses across endemic areas of scorpionism
ArticleAbstract: Scorpions of the Neotropical genus Tityus are responsible for most severe envenomations in the CaribPalabras claves:antivenom, Immunochemical, Neurotoxin, Scorpion, Tityus, venomAutores:Acosta H., Adolfo Borges, Angulo Y., Bonilla F., Caro-López J.A., Castillo A., De Sousa L., Gómez A., Gómez J.P., Graham M.R., Ishikawa E.A.Y., Lomonte B., Machado-de-Ávila R.A., Miranda R.J., Otero R., Pardal P.P.O., Pascale J.M.Fuentes:scopusSnake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management
ArticleAbstract: We describe two geographically differentiated venom phenotypes across the wide distribution range ofPalabras claves:BOTHROPS ATROX, Geographic venom variability, Mass spectrometry, N-terminal sequence, Paedomorpohism, Snake population venomics, Snake venom proteomicsAutores:Adolfo Borges, Angulo Y., Calvete J.J., Chalkidis H.M., Furtado M.F.D., Gutiérrez J.M., Lomonte B., Moura-Da-Silva A.M., Mourão R.H.V., Pérez A., Sanz L., Vargas A.M.Fuentes:scopusSnake venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal in South America
ArticleAbstract: We report a comparative venomic and antivenomic characterization of the venoms of newborn and adultPalabras claves:Antibothropic and anticrotalic ABC antivenom, Antivenomics, Crotalus durissus, Crotalus simus, Crotoxin, Ontogenetic shift, Paedomorphism, Polyvalent (crotalinae) ICP antivenom, Snake venom protein families, Snake venomicsAutores:Adolfo Borges, Alape-Girón A., Angulo Y., Bremo A., Calvete J.J., Cid P., De La Torre P., Dos-Santos M.C., Flores-Díaz M., Gutiérrez J.M., Lomonte B., Sanz L.Fuentes:scopus