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Article(3)
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Amino Acids(1)
Bioorganic and Medicinal Chemistry Letters(1)
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scopus(3)
A BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug
ArticleAbstract: Therapeutic application of many drugs is often hampered by poor or denied access to intracellular taPalabras claves:BODIPY, cell-penetrating peptide, Dual fluorescent labeling, Miltefosine, Monitoring of intracellular drug delivery, Reversion of resistanceAutores:Abengózar M.Á., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Luque-Ortega J.R., Rivas L., Ulises Acuña A.Fuentes:scopusDefeating Leishmania resistance to Miltefosine (hexadecylphosphocholine) by peptide-mediated drug smuggling: A proof of mechanism for trypanosomatid chemotherapy
ArticleAbstract: Miltefosine (hexadecylphosphocholine, HePC), the first orally active drug successful against leishmaPalabras claves:cell-penetrating peptide, LEISHMANIA, Miltefosine, Resistance reversion, Tat, TrypanosomaAutores:Acuña A.U., Amat-Guerri F., Andreu D., B. G. De la Torre, Bart J.M., Hornillos V., Luque-Ortega J.R., Navarro M., Rivas L., Rueda C.Fuentes:scopusSynthesis of 16-mercaptohexadecylphosphocholine, a miltefosine analog with leishmanicidal activity
ArticleAbstract: The alkylphosphocholine miltefosine (n-hexadecylphosphocholine, MT) has been introduced recently asPalabras claves:Hexadecylphosphocholine, LEISHMANIA, Mercaptophosphocholine, Miltefosine, ParasiticideAutores:Acuña A.U., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Rivas L., Saugar J.M.Fuentes:scopus