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Bio-analytical method based on MALDI-MS analysis for the quantification of CIGB-300 anti-tumor peptide in human plasma
ArticleAbstract: A fully validated bio-analytical method based on Matrix-Assisted-Laser-Desorption/Ionization-Time ofPalabras claves:Anti-tumor peptide, Bio-analytical method, Full validation, Human plasma, Maldi-tofAutores:Audain E., B. G. De la Torre, Besada-Pérez V., Cabrales-Rico A., Garay H.E., Gómez J.A., González L.J., Machado Y.J., Marcelo J.L., Morales O., Perea-Rodríguez S.E., Perera Y., Reyes O., Reyes V.Fuentes:scopusCIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
ArticleAbstract: Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, wPalabras claves:apoptosis, Cancer targeted therapy, Casein kinase 2Autores:Acevedo B.E., Alonso D.F., Ariosa J., Bacardí D.M., Baladron I., Besada-Pérez V., Betancourt L., Castellanos L.R., Cosme K., Cruz M., Díaz A., Falcón-Cama V., Farina H., Garay H.E., Gil J., Gómez D., Gómez R., González L.J., Hernández I., Herrera L., López C., López-Mola E., López-Saura P.A., Marcelo J.L., Mendoza O., Perea-Rodríguez S.E., Perera Y., Puchades Y., Reyes O., Rodriguez A., Sánchez A., Santana A., Serrano J.M., Sigman H., Silva R., Solares M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopus