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Characterization of amyloid-β granules in the hippocampus of SAMP8 mice
ArticleAbstract: The senescence accelerated mouse-prone 8 (SAMP8) strain of mice is an experimental model of acceleraPalabras claves:Alzheimer's disease, Amyloid-β, hippocampus, HSPG, MAP-2, SAMP8, syndecan, TauAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Mercader C., Pallás M., Vilaplana J.Fuentes:scopus(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
ArticleAbstract: Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of AlzPalabras claves:acetylcholinesterase inhibitors, Cerebellar granule cells, colchicine, neuronal death, RATAutores:Antoni Camins, Camps P., Canudas A.M., Jiménez A., Jordá E.G., Muñoz-Torrero D., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopusDendritic spine abnormalities in hippocampal CA1 pyramidal neurons underlying memory deficits in the SAMP8 mouse model of Alzheimer's disease
ArticleAbstract: SAMP8 is a strain of mice with accelerated senescence. These mice have recently been the focus of atPalabras claves:Alzheimer's disease, Dendrites, Learning, MEMORY, object recognition test, SAMP8, Senescence, synaptophysinAutores:Antoni Camins, Bayod S., Del Valle J., González-Burgos I., Pallás M., Velázquez-Zamora D.A., Zárate C.B.Fuentes:scopusEvaluation of neuropathological effects of a high-fat diet in a presymptomatic Alzheimer's disease stage in APP/PS1 mice
ArticleAbstract: Alzheimer's disease (AD) is currently an incurable aging-related neurodegenerative disorder. RecentPalabras claves:Alzheimer's disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Alva N., Antoni Camins, Auladell C., Carbonell T., Ettcheto M., Folch J., Pallás M., Pedros I., Petrov D., Zárate C.B.Fuentes:scopusEarly amyloid accumulation in the hippocampus of SAMP8 mice
ArticleAbstract: Late-onset Alzheimer's disease (AD) is the most common form of AD appearing after 65 years of age. TPalabras claves:aging, Alzheimer's disease, Amyloid-β, Aβ40, Aβ42, AβPP, hippocampus, SAMP8, SAMR1, SenescenceAutores:Antoni Camins, Casadesús G., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopusNeuronal cell cycle re-entry markers are altered in the senescence accelerated mouse P8 (SAMP8)
ArticleAbstract: Senescence-accelerated mice 8 (SAMP8), a model of aging, display many established pathological featuPalabras claves:aging, Alzheimer's disease, CDK5, cell cycle, GSK3β, TauAutores:Antoni Camins, Casadesús G., Gutiérrez-Cuesta J., Jiménez A., Lee H.g., Ortuo-Sahagún D., Pallás M., Smith M.A., Tajes M.Fuentes:scopusNeuroprotective effects of the amylin analog, pramlintide, on Alzheimer's disease are associated with oxidative stress regulation mechanisms
ArticleAbstract: Administration of the recombinant analog of the pancreatic amyloid amylin, Pramlintide, has shown thPalabras claves:Alzheimer's disease, amylin, metabolism, neuroprotection, Oxidative Stress, pramlintideAutores:Antoni Camins, Blair J., Casadesús G., Corrigan R., Grizzanti J., Lee H.g., Mey M., Pallás M., Patrick S.Fuentes:scopusNeuroprotective role of trans-resveratrol in a murine model of familial alzheimer's disease
ArticleAbstract: The amyloid-β protein precursor/presenilin 1 (AβPP/PS1) mouse model of Alzheimer's disease (AD) hasPalabras claves:AMPK, inflammation, Mitochondria, Resveratrol, Sirtuin 1Autores:Antoni Camins, Del Valle J., Ferrer I., Griñan-Ferré C., Pallás M., Porquet D., Sanfeliu C.Fuentes:scopusLong-term exercise modulates hippocampal gene expression in senescent female mice
ArticleAbstract: The senescence-accelerated SAMP8 mouse is considered a useful non-transgenic model for studying aspePalabras claves:aging, Alzheimer's disease, BRAIN, Exercise, Gene, Long-term, Mice, Microarrays, SAMP8, voluntaryAutores:Alvarez-López M.J., Antoni Camins, Castro-Freire M., Cosín-Tomás M., Del Valle J., Escorihuela R.M., Kaliman P., Lalanza J.F., Pallás M., Párrizas M., Sanchez-Roige S.Fuentes:scopus