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scopus(24)
Editorial: Safety pharmacology - risk assessment qt interval prolongation and beyond
OtherAbstract:Palabras claves:Cardiac electrophysiology, cardiotoxicity, Drug-induced arrhythmia, Multi-scale modeling, QT interval prolongationAutores:Esther Pueyo, Grandi E., Morotti S., Rodríguez B.Fuentes:scopusA multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis
ArticleAbstract: Enhanced temporal and spatial variability in cardiac repolarization has been related to increased arPalabras claves:Autores:Burrage K., Corrias A., Esther Pueyo, Jost N., Nánási P.P., Rodríguez B., Szél T., Szentandrássy N., Varro A., Virag L.Fuentes:scopusA new ECG biomarker for drug toxicity: A combined signal processing and computational modeling study
Conference ObjectAbstract: QT prolongation is the only clinically proven, yet insufficient, electrocardiogram (ECG) biomarker fPalabras claves:Autores:Esther Pueyo, Jie X., Rodríguez B.Fuentes:scopusTorsadogenic drug-induced increased short-term variability of JT-area
Conference ObjectAbstract: Increased beat-to-beat variability of repolarization (BVR) has been suggested to indicate increasedPalabras claves:Autores:Esther Pueyo, Jie X., Rodríguez B.Fuentes:scopusThe 'Digital Twin' to enable the vision of precision cardiology
ReviewAbstract: Providing therapies tailored to each patient is the vision of precision medicine, enabled by the incPalabras claves:Artificial intelligence, Computational Modelling, DIGITAL TWIN, Precision MedicineAutores:Bueno-Orovio A., Bukhari H.A., Cornelussen R., Corral-Acero J., Delhaas T., DiAchille P., Doltra A., Esther Pueyo, Feng Y., Fernandes J.F., Geris L., Gilbert A., Grau V., Gurev V., Hongxing Luo, Lamata P., Leeson P., Loncaric F., Luo H., Marciniak M., Margara F., Martinez M.V., Mayr M., McLeod K., Morrison T., Mortier P., Niederer S., Pathmanathan P., Potse M., Prinzen F., Remme E.W., Rodero C., Rodríguez B., Santos M.S., Shamohammdi M., Sitges M., Vigmond E.J., Wajdan A., Westphal P., Zacur E.Fuentes:scopusThe Na +K + pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue
ArticleAbstract: Pharmacological treatment of atrial fibrillation (AF) exhibits limited efficacy. Further developmentPalabras claves:Action potential, Antiarrhythmic agents, Atrium, In silico high-throughput screening, ReentryAutores:Bueno-Orovio A., Corrias A., Davies M., Esther Pueyo, Jacobson I., Jonathan Swinton, Pablo Laguna, Rodríguez B., Sanchez C., Swinton J.Fuentes:scopusAtrial fibrillation dynamics and ionic block effects in six Heterogeneous human 3D virtual atria with distinct repolarization dynamics
ArticleAbstract: Atrial fibrillation (AF) usually manifests as reentrant circuits propagating through the whole atriaPalabras claves:arrhythmia, Electrical propagation, electrophysiology, Fibrillatory patterns, Human atria, Model populations, variabilityAutores:Bueno-Orovio A., Esther Pueyo, Rodríguez B., Sanchez C.Fuentes:scopusCorrection: Experimentally-based computational investigation into beat-to-beat variability in ventricular repolarization and its response to ionic current inhibition (PLoS ONE (2016) 11:3 (e0151461) DOI: 10.1371/journal.pone.0151461)
OtherAbstract: The following information is missing from the Funding section: E.P. acknowledges the financial suppoPalabras claves:Autores:Britton O.J., Burrage K., Dangerfield C.E., Esther Pueyo, Jost N., Kistamás K., Nánási P.P., Rodríguez B., Szentandrássy N., Varro A., Virag L.Fuentes:scopusCardiac memory in human atria and relation to arrhythmogenesis
Conference ObjectAbstract: Abnormal adaptation of action potential duration (APD) to changes in heart rate (HR) has been suggesPalabras claves:Autores:Esther Pueyo, Pablo Laguna, Rodríguez B., Sanchez C.Fuentes:scopusCell repolarization variability modulates atrial fibrillation dynamics in 3D virtual human atria
Conference ObjectAbstract: Intersubject variability in cardiac electrophysiology might determine the patient-specific pronenessPalabras claves:Autores:Bueno-Orovio A., Esther Pueyo, Rodríguez B., Sanchez C.Fuentes:scopus