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Comparison of the Opn-CreER and Ck19-CreER drivers in bile ducts of normal and injured mouse livers
OtherAbstract: Inducible cyclization recombinase (Cre) transgenic mouse strains are powerful tools for cell lineagePalabras claves:Bile duct cells, Cholangiocytes, Ck19, Cre, Knockout, Lineage tracing, Mouse liver, OpnAutores:Grunsven L., Halder G., Huffel L., Ivánm Moya, Leclercq I., Lemaigre F.P., Lesaffer B., Verboven E.Fuentes:scopusHippo signaling instructs ectopic but not normal organ growth
ArticleAbstract: The Hippo signaling pathway is widely considered a master regulator of organ growth because of the pPalabras claves:Autores:Aerts S., Atkins M., de Waegeneer M., González-Blas C.B., Halder G., Hillen H., Iván M. Moya, Jacobs J., Johnson R.L., Kowalczyk W., Romanelli L., Sansores-Garcia L., Soheily S., van Grunsven L.A., Van Huffel L., Verboven E., Verhulst S., Xie J.Fuentes:googlescopusPeritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice
ArticleAbstract: The Hippo signaling pathway and its two downstream effectors, the YAP and TAZ transcriptional coactiPalabras claves:Autores:Aerts S., Algueró-Nadal A., Castaldo S.A., de Waegeneer M., Halder G., Hillen H., Iván M. Moya, Jacobs J., Johnson R.L., Karaman R., Karras P., Kowalczyk W., Mannaerts I., Marine J.C., Roskams T., Sansores-Garcia L., Soheily S., Van den Mooter L., van Grunsven L.A., van Haele M., Van Huffel L., Verboven E., Verhulst S., Xie J., Zender L.Fuentes:googlescopusRegeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis
ArticleAbstract: Background and Aims: The Hippo pathway and its downstream effectors YAP and TAZ (YAP/TAZ) are heraldPalabras claves:Biliary Epithelial Cells, Cholangiocytes, hippo pathway, Toxic InjuryAutores:Algueró-Nadal A., Bergers G., Castaldo S.A., Halder G., Hillen H., Iván M. Moya, Kowalczyk W., Lambrechts D., Lemaigre F.P., Mercader-Celma C., Romanelli L., Roskams T., Sansores-Garcia L., Soheily S., Souza N.A., Van Brussel T., van Grunsven L.A., Van Huffel L., Vella G., Verboven E., Verhulst S., Xie J.Fuentes:googlescopus