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Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks
ArticleAbstract: Extrasynaptic neurotransmission is an important short distance form of volume transmission (VT) andPalabras claves:Extrasynaptic, G protein coupled receptors, Heteromers, Neurotransmission, Receptor-receptor interactions, Striatal networks, Volume transmission, Wiring transissionAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Díaz-Cabiale Z., Ferraro L., Fuxe K., Garriga P., Guescini M., Narvaez J.A., Rivera A., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusFibroblast growth factor receptor 1 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity
ArticleAbstract: Background: The hippocampus and its 5-hydroxytryptamine transmission plays an important role in deprPalabras claves:allosteric modulation, Depression, Fibroblast growth factor receptor, Heteroreceptor, neuronal plasticity, serotonin receptorsAutores:Agnati L.F., Belluardo N., Borroto-Escuela D.O., Ciruela F., Di Liberto V., Fuxe K., Mudó G., Narváez M., Pérez-Alea M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusG protein-coupled receptor heterodimerization in the Brain
Book PartAbstract: G protein-coupled receptors (GPCRs) play critical roles in cellular processes and signaling and havePalabras claves:allosteric modulation, Depression, Fibroblast growth factor receptor, neuronal plasticity, Receptor heterocomplex, serotonin receptorsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Garriga P., Narváez M., Palkovits M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusGPCR heteromers and their allosteric receptor-receptor interactions
ArticleAbstract: The concept of intramembrane receptor-receptor interactions and evidence for their existences were iPalabras claves:Adenosine receptor, allosteric modulation, Dopamine receptors, GPCR, moonlighting, Oligomers, Receptor G protein coupling, Receptor interface, Receptor mosaic, Receptor recognition, Receptor signaling, Receptor trafficking, Triplet homologiesAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Ferraro L., Filip M., Frankowska M., Fuxe K., Guidolin D., Marcellino D., Tanganelli S., Tarakanov A.O., W. Romero-Fernandez, Woods A.S.Fuentes:scopusDiversity and bias through receptor-receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization
ReviewAbstract: Allosteric receptor-receptor interactions in GPCR heteromers appeared to introduce an intermolecularPalabras claves:allosteric modulation, Biased recognition, Biased signaling, G protein-coupled receptor, Heterodimerization, Receptor diversity, Receptor heterodimers, Receptor-receptor interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Díaz-Cabiale Z., Ferraro L., Filip M., Fuxe K., Garriga P., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusCharacterization of the A<inf>2A</inf>R-D<inf>2</inf>R interface: Focus on the role of the C-terminal tail and the transmembrane helices
ArticleAbstract: A single serine point mutation (S374A) in the adenosine A2A receptor (A2AR) C-terminal tail reducesPalabras claves:Adenosine A receptor 2A, Dopamine D receptor 2, G protein coupled receptors, Heteromerization, Protein-protein interaction, Transmembrane segmentsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Corrales F., Flajolet M., Frankowska M., Fuxe K., Gómez-Soler M., Heintz N., Marcellino D., Narváez M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusAgonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family
ArticleAbstract: Fibroblast growth factor receptor 1 (FGFR1) is known to be activated by homodimerization in the presPalabras claves:BRET, FGFR1, Fibroblast growth factors, Homodimerization, MAPKAutores:Agnati L.F., Belluardo N., Borroto-Escuela D.O., Ciruela F., Fuxe K., Mudó G., Narváez M., Pérez-Alea M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D2 and 5-hydroxytryptamine 5-HT<inf>2A</inf> receptors assemble into functionally interacting heteromers
ArticleAbstract: In view of the co-distribution of dopamine D2LR and 5-hydroxytryptamine 5-HT2A receptors (D2LR and 5Palabras claves:allosteric modulation, Dopamine D R receptor 2, G protein-coupled receptors, Heteromerization, protein-protein interactions, Serotonin 5-HT receptor 2AAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Marcellino D., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D2 and D4 receptor heteromerization and its allosteric receptor-receptor interactions
ArticleAbstract: Dopamine D2 and D4 receptors partially codistribute in the dorsal striatum and appear to play a fundPalabras claves:allosteric modulation, Dopamine D R receptor 2, Dopamine D R receptor 4, G protein-coupled receptors, Heteromerization, Protein-protein interactions.Autores:Agnati L.F., Borroto-Escuela D.O., Craenenbroeck K.V., Fuxe K., Guidolin D., Haegeman G., Rivera A., Tarakanov A.O., W. Romero-Fernandez, Woods A.S.Fuentes:scopusDopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: Novel targets for antipsychotic drugs
Book PartAbstract: This review is focused on the D2 heteroreceptor complexes within the ventral striatum with their recPalabras claves:D2 receptors, Heteroreceptor complexes, Receptor-receptor interactions, Schizophrenia, Ventral striatumAutores:Agnati L.F., Borroto-Escuela D.O., Di Palma M., Ferraro L., Fuxe K., Pérez-Alea M., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopus