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Diversity and bias through receptor-receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization
ReviewAbstract: Allosteric receptor-receptor interactions in GPCR heteromers appeared to introduce an intermolecularPalabras claves:allosteric modulation, Biased recognition, Biased signaling, G protein-coupled receptor, Heterodimerization, Receptor diversity, Receptor heterodimers, Receptor-receptor interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Díaz-Cabiale Z., Ferraro L., Filip M., Fuxe K., Garriga P., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: Novel targets for antipsychotic drugs
Book PartAbstract: This review is focused on the D2 heteroreceptor complexes within the ventral striatum with their recPalabras claves:D2 receptors, Heteroreceptor complexes, Receptor-receptor interactions, Schizophrenia, Ventral striatumAutores:Agnati L.F., Borroto-Escuela D.O., Di Palma M., Ferraro L., Fuxe K., Pérez-Alea M., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusMoonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field
ReviewAbstract: There is serious interest in understanding the dynamics of the receptor-receptor and receptor-proteiPalabras claves:G protein-coupled receptors, Heterodimerization, moonlighting, neuropsychiatric disorders, neurotherapeutic targets, receptorreceptor interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Palkovits M., Tarakanov A.O., W. Romero-FernandezFuentes:scopus