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Biomedical Papers(1)
Cancer Chemotherapy and Pharmacology(1)
European Journal of Pharmacology(1)
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scopus(6)
Cytotoxic activity of seco-entkaurenes from Croton caracasana on human cancer cell lines
ArticleAbstract: In the course of searching for bioactive compounds from Croton species from Venezuela, two seco-entkPalabras claves:Croton caracasana, Cytotoxic, euphorbiaceae, seco-entkaurenesAutores:Alírica Isabel Suárez, Arvelo F.A., Chavez K., Compagnone R.S., de Sanctis J.B., Mateu E., Mijares M.R., Muñoz A., Sojo F.J.Fuentes:scopusCytotoxic effects of fisturalin-3 and 11-Deoxyfisturalin-3 on Jurkat and U937 cell lines
ArticleAbstract: Background. Fisturalines are bromotyrosine compounds isolated from marine sponges. Previous studiesPalabras claves:11-deoxyfistularin-3, Aplysina fistularis, Bromotyrosine, Cáncer, Fistularin-3, Leukemia, quercetinAutores:Alírica Isabel Suárez, Avila R., Barroeta A., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R., Ochoa M.Fuentes:scopusCaracasine acid, an ent-3,4-seco-kaurene, promotes apoptosis and cell differentiation through NFkB signal pathway inhibition in leukemia cells.
ArticleAbstract: Caracasine acid (CA) is an ent-3,4-seco-kaurene isolated from the plant Croton micans. Decreased canPalabras claves:Annexin-V, apoptosis, Cáncer, Caracasine acid, Croton, Kaurene compounds, Leukemia, NF-κBAutores:Alírica Isabel Suárez, Chavez K., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R.Fuentes:scopusMetabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches
ReviewAbstract: The constant changes in cancer cell bioenergetics are widely known as metabolic repro-gramming. ReprPalabras claves:Carbohydrates, Energy metabolism, immunotherapy, inflammation, Metabolic reprogramming, neoplasms, tumor microenvironmentAutores:de Sanctis J.B., Galbán N., Garrido B., González M.C., Navarro C., Ortega A., Santeliz R., Valmore Bermúdez, Vera I.Fuentes:scopusThe marine sponge toxin agelasine B increases the intracellular Ca <sup>2+</sup> concentration and induces apoptosis in human breast cancer cells (MCF-7)
ArticleAbstract: Purpose: In search for new drugs derived from natural products for the possible treatment of cancer,Palabras claves:Agelasine B, calcium, Natural products, SERCA, ThapsigarginAutores:Alírica Isabel Suárez, Arvelo F.A., Benaím G., Chirino P., Colman L., Compagnone R.S., de Sanctis J.B., Dipolo R., Felibertt P., Galindo-Castro I., Mayora A., Pimentel A.A., Rojas H., Silva M.L., Sojo F.J.Fuentes:scopusThe yap/taz signaling pathway in the tumor microenvironment and carcinogenesis: Current knowledge and therapeutic promises
ReviewAbstract: The yes-associated protein (YAP) and the transcriptional coactivator with PDZ-binding motif (TAZ) arPalabras claves:Carcinogenesis, cell proliferation, Chemoresistance, Drug resistance, Hippo signaling pathway, immunotherapy, Neoplastic stem cells, TEAD, tumor microenvironment, YAP/TAZAutores:de Sanctis J.B., Diaz M.P., Navarro C., Ortega A., Parra H., Rojas M., Salazar-Vílchez J., Torres W., Valmore Bermúdez, Vera I.Fuentes:scopus