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Associations of Early Systolic Blood Pressure Control and Outcome after Thrombolysis-Eligible Acute Ischemic Stroke: Results from the ENCHANTED Study
ArticleAbstract: Background and Purpose: In thrombolysis-eligible patients with acute ischemic stroke, there is uncerPalabras claves:Blood pressure, Hypertension, intracranial hemorrhage, Ischemic strokeAutores:Anderson C.S., Arima H., Bath P.M.W., Broderick J.P., Chalmers J., Chen G., Chen X., Delcourt C., Demchuk A.M., Donnan G.A., Durham A.C., Lavados P.M., Lee T.H., Levi C., Lindley R.I., Luca Di Tanna G., Martins S.O., Minhas J.S., Moullaali T.J., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., Sato S., Sharma V.K., Silva-Sieger F.A., Song L., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopusApplicability of ENCHANTED trial results to current acute ischemic stroke patients eligible for intravenous thrombolysis in England and Wales: Comparison with the Sentinel Stroke National Audit Programme registry
ArticleAbstract: Background: Randomized controlled trials provide high-level evidence, but the necessity to include sPalabras claves:acute ischemic stroke, Alteplase, Clinical trial, health outcomes, thrombolysisAutores:Arima H., Bath P.M.W., Bray B.D., Broderick J.P., Chalmers J., Durham A.C., Kim J.S., Lavados P.M., Lee T.H., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Paley L., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., Rudd A.G., S Anderson C., Sharma V.K., Sprigg N., Wang J.G., Wang X., Woodward M.Fuentes:scopusEffects of intensive blood pressure lowering on cerebral ischaemia in thrombolysed patients: insights from the ENCHANTED trial
ArticleAbstract: Background: Intensive blood pressure lowering may adversely affect evolving cerebral ischaemia. We aPalabras claves:Acute ischaemic stroke, Blood pressure, Brain imaging, Cerebral infarction, Clinical trial, thrombolysisAutores:Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Chen C., Chen X., Delcourt C., Demchuk A.M., Donnan G.A., Lavados P.M., Levi C., Li G., Li Q., Lindley R.I., Liu L., Mair G., Martins S.O., Octavio Marques Pontes-Neto, Olavarria V.V., Ong S., Ouyang M., Parsons M.W., Robinson T.G., S Anderson C., Song L., Venturelli P.M., Wang X., Wardlaw J.M., Zhang G., Zhang L.Fuentes:scopusOxygen desaturation and adverse outcomes in acute stroke: Secondary analysis of the HeadPoST study
ArticleAbstract: Objective: Uncertainty exists over the prognostic significance of low arterial oxygen saturation (SaPalabras claves:Acute stroke, Clinical trial, Disability, head position, oxygen saturationAutores:Anderson C.S., Billot L., Brunser A.M., Hackett M.L., Lavados P.M., Lee T.H., Middleton S., Octavio Marques Pontes-Neto, Olavarria V.V., Ouyang M., Robinson T.G., Roffe C., Song L., Venturelli P.M., Wang X., Watkins C.L.Fuentes:scopusInfluence of Renal Impairment on Outcome for Thrombolysis-Treated Acute Ischemic Stroke: ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) Post Hoc Analysis
ArticleAbstract: Background and Purpose - Renal dysfunction (RD) is associated with poor prognosis after stroke. We aPalabras claves:Glomerular Filtration Rate, Hypertension, intracranial hemorrhages, ODDS RATIO, strokeAutores:Carr S.J., Chalmers J., Kim J.S., Lavados P.M., Lee T.H., Lindley R.I., Octavio Marques Pontes-Neto, Olavarria V.V., Ricci S., Robinson T.G., Rodriguez J.A., S Anderson C., Sato S., Sharma V.K., Wang X., Woodward M.Fuentes:scopusInfluence of including Patients with Premorbid Disability in Acute Stroke Trials: The HeadPoST Experience
ArticleAbstract: Background: Patients with premorbid functional impairment are generally excluded from acute stroke tPalabras claves:Acute stroke, Acute stroke trials, Clinical outcomeAutores:Anderson C.S., Arima H., Billot L., Brunser A.M., Delcourt C., Hackett M.L., Lavados P.M., Middleton S., Moullaali T.J., Octavio Marques Pontes-Neto, Olavarria V.V., Ouyang M., Pandian J.D., Robinson T.G., Rogers K., Sandset E.C., Song L., Venturelli P.M., Wang X., Watkins C.L., Yang J.Fuentes:scopusLow-Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy the ENCHANTED Trial (Enhanced Control of Hypertension and Thrombolysis Stroke Study)
Conference ObjectAbstract: Background and Purpose'Many patients receiving thrombolysis for acute ischemic stroke are on prior aPalabras claves:aspirin, Brain Infarction, Hypertension, intracranial hemorrhages, Tissue plasminogen activatorAutores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Demchuk A.M., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sato S., Sharma V.K., Wang J.G., Wang X., Woodward M.Fuentes:scopusLow-dose versus standard-dose intravenous alteplase in acute ischemic stroke
ArticleAbstract: BACKGROUND: Thrombolytic therapy for acute ischemic stroke with a lower-than-standard dose of intravPalabras claves:Autores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Cao Y., Chalmers J., Chen G., Chen X., Demchuk A.M., Donnan G.A., Huang Y., Kim J.S., Lavados P.M., Lee T.H., Levi C., Li Q., Lindley R.I., Martins S.O., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., Roffe C., S Anderson C., Sharma V.K., Silva-Sieger F.A., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopusLow-dose vs standard-dose alteplase for patients with acute ischemic stroke: Secondary analysis of the ENCHANTED randomized clinical trial
ArticleAbstract: IMPORTANCE: A lower dose of intravenous alteplase appears to be a safer treatment option than the stPalabras claves:Autores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Demchuk A.M., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Li Q., Lindley R.I., Martins S.O., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sharma V.K., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopusLipid-lowering pretreatment and outcome following intravenous thrombolysis for acute ischaemic stroke: a post hoc analysis of the enhanced control of hypertension and thrombolysis stroke study trial
ArticleAbstract: Background: Debate exists as to whether statin pretreatment confers an increased risk of 90-day mortPalabras claves:Acute stroke outcome, Intracranial haemorrhage, Lipid-lowering therapy, OR, RISK FACTORS, statins, strokeAutores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Martins S.O., Minhas J.S., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Ricci S., Robinson T.G., S Anderson C., Sato S., Sharma V.K., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopus