Mostrando 10 resultados de: 46
Filtros aplicados
Publisher
British Journal of Pharmacology(4)
Molecular Neurobiology(3)
Apoptosis(2)
Experimental Gerontology(2)
International Journal of Molecular Sciences(2)
Área temáticas
Enfermedades(39)
Fisiología humana(30)
Farmacología y terapéutica(12)
Sistemas fisiológicos específicos de los animales(10)
Bioquímica(8)
Área de conocimiento
Neurología(37)
Biología celular(12)
Biología molecular(5)
Biología del desarrollo(2)
Apoptosis(1)
Origen
scopus(46)
Antiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine in cerebellar granule cells deprived of serum and potassium: A cell cycle-related mechanism
ArticleAbstract: Neuronal apoptosis may be partly due to inappropriate control of the cell cycle. We used serum depriPalabras claves:apoptosis, Caspase-3, cell cycle, cyclin, E2F-1, RoscovitineAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Verdaguer E.Fuentes:scopusAntiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells
ArticleAbstract: In the present study dopaminergic neuroblastoma B65 cells were exposed to Camptothecin (CPT) (0.5-10Palabras claves:Ataxia telangiectasia mutated, camptothecin, cell cycle, RoscovitineAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopus(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
ArticleAbstract: Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of AlzPalabras claves:acetylcholinesterase inhibitors, Cerebellar granule cells, colchicine, neuronal death, RATAutores:Antoni Camins, Camps P., Canudas A.M., Jiménez A., Jordá E.G., Muñoz-Torrero D., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopusA metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusCorrigendum to “Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6 J mice. A potential model of sporadic Alzheimer's disease” [J. Mech. Ageing Dev. 162 (March) (2017) 38-45](S0047637416300859)(10.1016/j.mad.2016.11.002)
OtherAbstract: The authors regret that there are some errors in the original Figures 2, 3 and 5. A reader brought tPalabras claves:Autores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusCyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons
ArticleAbstract: 1 Cyclosporin A (CsA, 1-50 μM), an immunosuppressive drug with known neurotoxic effects, did not decPalabras claves:CDK5, colchicine, Cyclosporin A, flavopiridol, Neurotoxicity, RoscovitineAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopusGSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons
ArticleAbstract: In the present study, we evaluated the effects of roscovitine (Rosco) and flavopiridol (Flavo), bothPalabras claves:apoptosis, Cerebellar granular cells, flavopiridol, GSK3β, RoscovitineAutores:Antoni Camins, Auladell C., de la Torre A.V., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusGlutamate excitotoxicity activates the MAPK/ERK signaling pathway and induces the survival of rat hippocampal neurons in vivo
ArticleAbstract: Current knowledge concerning the molecular mechanisms of the cellular response to excitotoxic insultPalabras claves:glutamate, hippocampus, MAPK/ERK, neuroprotection, NeurotoxicityAutores:Antoni Camins, González R.M., Huerta V.C., Lemus L., Ortuo-Sahagún D., Rivera-Cervantes M.C., Torres-Mendoza B.M., Verdaguer E., Zárate C.B.Fuentes:scopusErratum: Differences in activation of ERK1/2 and p38 kinase in Jnk3 null mice following KA treatment (Journal of Neurochemistry (2010) 114 (1315-1322))
OtherAbstract:Palabras claves:Autores:Antoni Camins, Auladell C., De Lemos M.L., Ferrer I., Folch J., Junyent F., Pallás M., Romero R., Verdaguer E.Fuentes:scopus