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Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release
ArticleAbstract: Augmentation of immunogenicity can be achieved by particulate delivery of an antigen and by its co-aPalabras claves:adjuvant, CpG, R848, Resiquimod, Synthetic nanoparticle vaccine, TLR agonistAutores:Altreuter D.H., Basto P.A., Browning E.A., Farokhzad O.C., Frank Alexis, Iannacone M., Ilyinskii P.O., Johnston L.P.M., Kishimoto T.K., Langer R.S., O'Neil C.P., Pittet L.A., Radovic-Moreno A.F., Roy C.J., Shi J., Tonti E., von Andrian U.H.Fuentes:scopusEngineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection
ArticleAbstract: Figure Persented: One of the major challenges in the development of targeted nanoparticles (NPs) forPalabras claves:aptamer, in vitro selection, Internalization, Nanoparticles, targeted cancer therapyAutores:Chan J.M., Cheng J., Digga E., Farokhzad O.C., Frank Alexis, Langer R.S., Levy-Nissenbaum E., Lupták A., Shi J., Teply B.A., Xiao Z.Fuentes:scopus