Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release

Article

Abstract: Augmentation of immunogenicity can be achieved by particulate delivery of an antigen and by its co-a

Palabras claves:

adjuvant, CpG, R848, Resiquimod, Synthetic nanoparticle vaccine, TLR agonist

Autores:

Altreuter D.H., Basto P.A., Browning E.A., Farokhzad O.C., Frank Alexis, Iannacone M., Ilyinskii P.O., Johnston L.P.M., Kishimoto T.K., Langer R.S., O'Neil C.P., Pittet L.A., Radovic-Moreno A.F., Roy C.J., Shi J., Tonti E., von Andrian U.H.

Fuentes:

scopus