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Article(13)
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scopus(13)
A BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug
ArticleAbstract: Therapeutic application of many drugs is often hampered by poor or denied access to intracellular taPalabras claves:BODIPY, cell-penetrating peptide, Dual fluorescent labeling, Miltefosine, Monitoring of intracellular drug delivery, Reversion of resistanceAutores:Abengózar M.Á., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Luque-Ortega J.R., Rivas L., Ulises Acuña A.Fuentes:scopusDefeating Leishmania resistance to Miltefosine (hexadecylphosphocholine) by peptide-mediated drug smuggling: A proof of mechanism for trypanosomatid chemotherapy
ArticleAbstract: Miltefosine (hexadecylphosphocholine, HePC), the first orally active drug successful against leishmaPalabras claves:cell-penetrating peptide, LEISHMANIA, Miltefosine, Resistance reversion, Tat, TrypanosomaAutores:Acuña A.U., Amat-Guerri F., Andreu D., B. G. De la Torre, Bart J.M., Hornillos V., Luque-Ortega J.R., Navarro M., Rivas L., Rueda C.Fuentes:scopusActivity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: Molecular basis for the differential mechanisms of action
ArticleAbstract: Acinetobacter baumannii has successfully developed resistance against all common antibiotics, includPalabras claves:Autores:Andreu D., B. G. De la Torre, Fernández-Reyes M., Pachón J., Pachón-Ibañez M.E., Rivas L., Rodríguez-Hernández M.J., Saugar J.M.Fuentes:scopusEssential Role of Enzymatic Activity in the Leishmanicidal Mechanism of the Eosinophil Cationic Protein (RNase 3)
ArticleAbstract: The recruitment of eosinophils into Leishmania lesions is frequently associated with a favorable evoPalabras claves:Antimicrobial peptide, cell-penetrating enzyme, membrane disruption, protozoa, RNaseAutores:Abengózar M.Á., Andreu D., B. G. De la Torre, Boix E., Fernández-Reyes M., Rivas L., Salazar V.A., Torrent M.Fuentes:scopusEfficacy of cecropin A-melittin peptides on a sepsis model of infection by pan-resistant Acinetobacter baumannii
ArticleAbstract: Pan-resistant Acinetobacter baumannii have prompted the search for therapeutic alternatives. We evalPalabras claves:Autores:Andreu D., B. G. De la Torre, Bengoechea J.A., Docobo-Pérez F., Fernández-Reyes M., López-Rojas R., March C., Pachón J., Pachón-Ibañez M.E., Rivas L.Fuentes:scopusInfluence of lysine N<sup>ε</sup>-trimethylation and lipid composition on the membrane activity of the cecropin A-melittin hybrid peptide CA(1-7)M(2-9)
ArticleAbstract: Although many studies have pointed out the promising role of antimicrobial peptides (AMPs) as therapPalabras claves:Autores:Andreu D., B. G. De la Torre, Bastos M., Coutinho A., Feio M.J., Rivas L., Teixeira V.Fuentes:scopusLysine N <sup>ε</sup>-trimethylation, a tool for improving the selectivity of antimicrobial peptides
ArticleAbstract: The effects of lysine N?-trimethylation at selected positions of the antimicrobial cecropin A?melittPalabras claves:Autores:Andreu D., B. G. De la Torre, Cabrales-Rico A., Díaz D., Fernández-Reyes M., Jiménez-Barbero J., Rivas L., Vallès-Miret M.Fuentes:scopusSequence inversion and phenylalanine surrogates at the β-Turn enhance the antibiotic activity of gramicidin S
ArticleAbstract: A series of gramicidin S (GS) analogues have been synthesized where the Phe (i + 1) and Pro (i + 2)Palabras claves:Autores:Andreu D., B. G. De la Torre, Cativiela C., Fernández-Reyes M., Jiménez A.I., Jiménez M.A., Rivas L., Santiveri C.M., Solanas C.Fuentes:scopusStructural framework for the modulation of the activity of the hybrid antibiotic peptide cecropin A-melittin [CA(1-7)M(2-9)] by N <sup>ε</sup>-lysine trimethylation
ArticleAbstract: The 3D structures of six linear pentadecapeptides derived from the cecropin A-melittin antimicrobialPalabras claves:Antimicrobial peptides (AMPs), cecropin A, membranes, NMR spectroscopy, TrimethyllysineAutores:Andreu D., B. G. De la Torre, Díaz M.D., Fernández-Reyes M., Jiménez-Barbero J., Rivas L.Fuentes:scopusStudies on the antimicrobial activity of cecropin A-melittin hybrid peptides in colistin-resistant clinical isolates of Acinetobacter baumannii
ArticleAbstract: Objectives: Acinetobacter baumannii has successfully developed resistance against all common antibioPalabras claves:A. baumannii, bactericidal activity, Capsule, colistin resistance, PolymyxinAutores:Andreu D., B. G. De la Torre, Docobo-Pérez F., Fernández-Cuenca F., García-Curiel A., Pachón J., Pachón-Ibañez M.E., Rivas L., Rodríguez-Hernández M.J., Saugar J.M.Fuentes:scopus